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Versatile Effects of GABA Oolong Tea on Improvements in Diastolic Blood Pressure, Alpha Brain Waves, and Quality of Life

Emerging evidence has demonstrated that using a new manufacturing technology to produce γ-aminobutyric acid (GABA)-fortified oolong (GO) tea could relieve human stress and exert versatile physiological benefits. The purpose of this human study was to investigate the therapeutic effects of daily GO t...

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Autores principales: Lin, Chih-Cheng, Hsieh, Chih-Yu, Chen, Li-Fen, Chen, Yen-Chun, Ho, Tien-Hwa, Chang, Shao-Chin, Chang, Jia-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10670354/
https://www.ncbi.nlm.nih.gov/pubmed/38002159
http://dx.doi.org/10.3390/foods12224101
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author Lin, Chih-Cheng
Hsieh, Chih-Yu
Chen, Li-Fen
Chen, Yen-Chun
Ho, Tien-Hwa
Chang, Shao-Chin
Chang, Jia-Feng
author_facet Lin, Chih-Cheng
Hsieh, Chih-Yu
Chen, Li-Fen
Chen, Yen-Chun
Ho, Tien-Hwa
Chang, Shao-Chin
Chang, Jia-Feng
author_sort Lin, Chih-Cheng
collection PubMed
description Emerging evidence has demonstrated that using a new manufacturing technology to produce γ-aminobutyric acid (GABA)-fortified oolong (GO) tea could relieve human stress and exert versatile physiological benefits. The purpose of this human study was to investigate the therapeutic effects of daily GO tea consumption on improvements in blood pressure, relaxation-related brain waves, and quality of life (QOL) over a period of 28 consecutive days. Total polyphenols, major catechins, and free amino acids were analyzed via an HPLC assay. Changes in heart rate, blood pressure, α brain waves (index of relaxation), and the eight-item QOL score were investigated on days 0, 7, 14, 21, and 28. The chemical analysis results showed that GO tea contained the most abundant amino acids and GABA, contributing to the relaxation activity. Among all study participants, the daily consumption of GO tea could reduce systolic blood pressure on day 21 and diastolic blood pressure on day 28 (p < 0.05 for both). For participants with pre-hypertension, GO tea could effectively reduce heart rate and systolic and diastolic blood pressure on day 28 (p < 0.05). At the end of the study, incremental changes in alpha brain waves and QOL scores were also demonstrated (p < 0.05 for both). This study suggests that GO tea might potentially serve as a natural source for alternative therapy to improve blood pressure, stress relief, and QOL.
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spelling pubmed-106703542023-11-12 Versatile Effects of GABA Oolong Tea on Improvements in Diastolic Blood Pressure, Alpha Brain Waves, and Quality of Life Lin, Chih-Cheng Hsieh, Chih-Yu Chen, Li-Fen Chen, Yen-Chun Ho, Tien-Hwa Chang, Shao-Chin Chang, Jia-Feng Foods Article Emerging evidence has demonstrated that using a new manufacturing technology to produce γ-aminobutyric acid (GABA)-fortified oolong (GO) tea could relieve human stress and exert versatile physiological benefits. The purpose of this human study was to investigate the therapeutic effects of daily GO tea consumption on improvements in blood pressure, relaxation-related brain waves, and quality of life (QOL) over a period of 28 consecutive days. Total polyphenols, major catechins, and free amino acids were analyzed via an HPLC assay. Changes in heart rate, blood pressure, α brain waves (index of relaxation), and the eight-item QOL score were investigated on days 0, 7, 14, 21, and 28. The chemical analysis results showed that GO tea contained the most abundant amino acids and GABA, contributing to the relaxation activity. Among all study participants, the daily consumption of GO tea could reduce systolic blood pressure on day 21 and diastolic blood pressure on day 28 (p < 0.05 for both). For participants with pre-hypertension, GO tea could effectively reduce heart rate and systolic and diastolic blood pressure on day 28 (p < 0.05). At the end of the study, incremental changes in alpha brain waves and QOL scores were also demonstrated (p < 0.05 for both). This study suggests that GO tea might potentially serve as a natural source for alternative therapy to improve blood pressure, stress relief, and QOL. MDPI 2023-11-12 /pmc/articles/PMC10670354/ /pubmed/38002159 http://dx.doi.org/10.3390/foods12224101 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Lin, Chih-Cheng
Hsieh, Chih-Yu
Chen, Li-Fen
Chen, Yen-Chun
Ho, Tien-Hwa
Chang, Shao-Chin
Chang, Jia-Feng
Versatile Effects of GABA Oolong Tea on Improvements in Diastolic Blood Pressure, Alpha Brain Waves, and Quality of Life
title Versatile Effects of GABA Oolong Tea on Improvements in Diastolic Blood Pressure, Alpha Brain Waves, and Quality of Life
title_full Versatile Effects of GABA Oolong Tea on Improvements in Diastolic Blood Pressure, Alpha Brain Waves, and Quality of Life
title_fullStr Versatile Effects of GABA Oolong Tea on Improvements in Diastolic Blood Pressure, Alpha Brain Waves, and Quality of Life
title_full_unstemmed Versatile Effects of GABA Oolong Tea on Improvements in Diastolic Blood Pressure, Alpha Brain Waves, and Quality of Life
title_short Versatile Effects of GABA Oolong Tea on Improvements in Diastolic Blood Pressure, Alpha Brain Waves, and Quality of Life
title_sort versatile effects of gaba oolong tea on improvements in diastolic blood pressure, alpha brain waves, and quality of life
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10670354/
https://www.ncbi.nlm.nih.gov/pubmed/38002159
http://dx.doi.org/10.3390/foods12224101
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