Cargando…

LCMR1 Promotes Large-Cell Lung Cancer Proliferation and Metastasis by Downregulating HLA-Encoding Genes

SIMPLE SUMMARY: LCMR1 is a subunit of the mediator complex, also known as MED19, which is involved in various life activities and is closely related to the occurrence and development of tumors. In this study, we knocked down LCMR1 in large cell lung cancer cells and found that high expression of LCM...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Lu, Li, Chunsun, Wu, Zhen, Li, Yanqin, Yu, Hang, Li, Tao, Wang, Yueming, Zhao, Wei, Chen, Liangan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10670470/ https://www.ncbi.nlm.nih.gov/pubmed/38001705 http://dx.doi.org/10.3390/cancers15225445

Ejemplares similares

Overexpression of LCMR1 is significantly associated with clinical stage in human NSCLC
por: Chen, Liangan, et al.
Publicado: (2011)

Deletion of LCMR1 in alveolar type II cells induces lethal impairment of lung structure and function in adult mice
por: Wang, Yueming, et al.
Publicado: (2023)

Inhibition of LCMR1 and ATG12 by demethylation-activated miR-570-3p is involved in the anti-metastasis effects of metformin on human osteosarcoma
por: Bao, Xing, et al.
Publicado: (2018)

Keratinocyte Growth Factor Gene Delivery via Mesenchymal Stem Cells Protects against Lipopolysaccharide-Induced Acute Lung Injury in Mice
por: Chen, Jie, et al.
Publicado: (2013)

Development of a DNA microarray assay for rapid detection of fifteen bacterial pathogens in pneumonia
por: Ma, Xiuqing, et al.
Publicado: (2020)

Downregulation of miR-637 promotes proliferation and metastasis by targeting Smad3 in keloids
por: Zhang, Ye, et al.
Publicado: (2018)

Perfluorocarbon reduces cell damage from blast injury by inhibiting signal paths of NF-κB, MAPK and Bcl-2/Bax signaling pathway in A549 cells
por: Zhang, Zhaorui, et al.
Publicado: (2017)

[Corrigendum] Downregulation of miR‑637 promotes proliferation and metastasis by targeting Smad3 in keloids
por: Zhang, Ye, et al.
Publicado: (2023)

Downregulation of lncRNA RPLP0P2 inhibits cell proliferation, invasion and migration, and promotes apoptosis in colorectal cancer
por: Yuan, Hang, et al.
Publicado: (2021)

Downregulation of PTPRK Promotes Cell Proliferation and Metastasis of NSCLC by Enhancing STAT3 Activation
por: Xu, Xuting, et al.
Publicado: (2019)

Development of a diagnostic model for malignant solitary pulmonary nodules based on radiomics features
por: Zhao, Wei, et al.
Publicado: (2022)

Downregulation of FEM1C enhances metastasis and proliferation in colorectal cancer
por: Huang, Runqing, et al.
Publicado: (2021)

Correlation between PD-L1 expression and radiomic features in early-stage lung adenocarcinomas manifesting as ground-glass nodules
por: Shi, Wenjia, et al.
Publicado: (2022)

EYA2 promotes lung cancer cell proliferation by downregulating the expression of PTEN
por: Li, Zhaoming, et al.
Publicado: (2017)

miR-3 Encoded by Hepatitis B Virus Downregulates PTEN Protein Expression and Promotes Cell Proliferation
por: Tang, Jian, et al.
Publicado: (2020)

HLA-C downregulation by HIV-1 adapts to host HLA genotype
por: Bachtel, Nathaniel D., et al.
Publicado: (2018)

Downregulation of Sprouty homolog 2 by microRNA-21 inhibits proliferation, metastasis and invasion, however promotes the apoptosis of multiple myeloma cells
por: WANG, JIN-HANG, et al.
Publicado: (2015)

HINT2 downregulation promotes colorectal carcinoma migration and metastasis
por: Li, Weihua, et al.
Publicado: (2017)

Inhibition of Cancer Cell Proliferation and Metastasis by Insulin Receptor Downregulation
por: Zhang, Hua, et al.
Publicado: (2010)

Downregulation of eukaryotic translation initiation factor 3b inhibited proliferation and metastasis of gastric cancer
por: Ma, Fang, et al.
Publicado: (2019)

NKX2-2 Suppresses Osteosarcoma Metastasis and Proliferation by Downregulating Multiple Target Genes
por: Chen, Huiming, et al.
Publicado: (2018)

TROAP Promotes Breast Cancer Proliferation and Metastasis
por: Li, Kai, et al.
Publicado: (2019)

MicroRNA-193a inhibits breast cancer proliferation and metastasis by downregulating WT1
por: Xie, FeiYan, et al.
Publicado: (2017)

Silencing SAPCD2 Represses Proliferation and Lung Metastasis of Fibrosarcoma by Activating Hippo Signaling Pathway
por: Zhu, Bowen, et al.
Publicado: (2020)

Downregulation of CDH11 Promotes Metastasis and Resistance to Paclitaxel in Gastric Cancer Cells
por: Yang, Zhongyin, et al.
Publicado: (2021)

MicroRNA-181a Inhibits Tumor Proliferation, Invasiveness, and Metastasis and Is Downregulated in Gastric Cancer
por: Lin, Feng, et al.
Publicado: (2015)

Downregulation of PSCA promotes gastric cancer proliferation and is related to poor prognosis
por: Xu, Li-pu, et al.
Publicado: (2020)

Downregulation of SLC27A6 by DNA Hypermethylation Promotes Proliferation but Suppresses Metastasis of Nasopharyngeal Carcinoma Through Modulating Lipid Metabolism
por: Zhong, Xuemin, et al.
Publicado: (2022)

VEGI downregulation is correlated with nodal metastasis and poor prognosis in lung adenocarcinoma
por: Xu, Yinhai, et al.
Publicado: (2021)

Downregulation of HNRNPK in human cancer cells inhibits lung metastasis
por: Li, Mengyuan, et al.
Publicado: (2019)

GFI1 downregulation promotes inflammation-linked metastasis of colorectal cancer
por: Xing, Wenjing, et al.
Publicado: (2017)

Diagnostic value of endobronchial ultrasound elastography in differentiating between benign and malignant hilar and mediastinal lymph nodes: a retrospective study
por: Wang, Yueming, et al.
Publicado: (2023)

RARγ-induced E-cadherin downregulation promotes hepatocellular carcinoma invasion and metastasis
por: Gan, Wen-Juan, et al.
Publicado: (2016)

MiR-223-3p promotes cell proliferation and metastasis by downregulating SLC4A4 in clear cell renal cell carcinoma
por: Xiao, Wen, et al.
Publicado: (2019)

Comparative analysis of serum total IgE levels and specific IgE levels in children aged 6 to 9 years with tic disorder and normal children
por: Liu, Yang, et al.
Publicado: (2023)

miR-339-5p inhibits cell migration and invasion in vitro and may be associated with the tumor-node-metastasis staging and lymph node metastasis of non-small cell lung cancer
por: LI, YUN, et al.
Publicado: (2014)

MicroRNA-432 is downregulated in osteosarcoma and inhibits cell proliferation and invasion by directly targeting metastasis-associated in colon cancer-1
por: Lv, Dengkun, et al.
Publicado: (2022)

Downregulation of MTAP promotes Tumor Growth and Metastasis by regulating ODC Activity in Breast Cancer
por: Zhang, Ying, et al.
Publicado: (2022)

Exogenous HMGB1 Promotes the Proliferation and Metastasis of Pancreatic Cancer Cells
por: Zhu, Li, et al.
Publicado: (2021)

Cloning and Expression Analysis of MEP Pathway Enzyme-encoding Genes in Osmanthus fragrans
por: Xu, Chen, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_llmme788rduc93k4fvburjk4r0