A Novel Co-Culture Model Reveals Enhanced CFTR Rescue in Primary Cystic Fibrosis Airway Epithelial Cultures with Persistent Pseudomonas aeruginosa Infection

People with cystic fibrosis (pwCF) suffer from chronic and recurring bacterial lung infections that begin very early in life and contribute to progressive lung failure. CF is caused by mutations in the CF transmembrane conductance regulator (CFTR) gene, which encodes an ion channel important for mai...

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Detalles Bibliográficos
Autores principales: Cholon, Deborah M., Greenwald, Matthew A., Higgs, Matthew G., Quinney, Nancy L., Boyles, Susan E., Meinig, Suzanne L., Minges, John T., Chaubal, Ashlesha, Tarran, Robert, Ribeiro, Carla M. P., Wolfgang, Matthew C., Gentzsch, Martina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10670530/
https://www.ncbi.nlm.nih.gov/pubmed/37998353
http://dx.doi.org/10.3390/cells12222618

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10670530/
https://www.ncbi.nlm.nih.gov/pubmed/37998353
http://dx.doi.org/10.3390/cells12222618

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