Cargando…

Multi-Asymmetric Irradiation Method Using a Ring Array to Obtain an Emission-Capable LED Beam Power Effect to Observe Cancer Removal Status in a Surgical Microscope

The light emitting diodes (LEDs) used in surgical fluorescence microscopes have weak power, to induce fluorescence emission. The LED induces fluorescence emission throughout a lesion due to its large beam width; however, the beam irradiation intensity is not uniform within the beam width, resulting...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Seon Min, Yoon, Kicheol, Lee, Sangyun, Ryu, Seung Yeob, Kim, Kwang Gi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10670550/
https://www.ncbi.nlm.nih.gov/pubmed/37998618
http://dx.doi.org/10.3390/diagnostics13223482
_version_ 1785149324389253120
author Lee, Seon Min
Yoon, Kicheol
Lee, Sangyun
Ryu, Seung Yeob
Kim, Kwang Gi
author_facet Lee, Seon Min
Yoon, Kicheol
Lee, Sangyun
Ryu, Seung Yeob
Kim, Kwang Gi
author_sort Lee, Seon Min
collection PubMed
description The light emitting diodes (LEDs) used in surgical fluorescence microscopes have weak power, to induce fluorescence emission. The LED induces fluorescence emission throughout a lesion due to its large beam width; however, the beam irradiation intensity is not uniform within the beam width, resulting in a fluorescence emission induction difference. To overcome this problem, this study proposes an asymmetric irradiation array for supplying power uniformly throughout the beam width of the LED and increasing the intensity of the LED. To increase the irradiation power of the LEDs, a multi-asymmetric irradiation method with a ring-type array structure was used. The LED consisted of eight rings, and the space between the LEDs, the placement position, and the placement angle were analyzed to devise an experimental method using 3D printing technology. To test the irradiation power of the LED, the working distance (WD) between the LED and target was 30 cm. The bias voltage of the LED for irradiating the light source was 5.0 V and the measured power was 4.63 mW. The brightness (lux) was 1153 lx. Consequently, the LED satisfied the fluorescence emission induction conditions. The diameter of the LED-irradiated area was 9.5 cm. Therefore, this LED could be used to observe fluorescent emission-guided lesions. This study maximized the advantages of LEDs with optimal conditions for fluorescence emission by increasing the beam width, irradiation area, and energy efficiency, using a small number of LEDs at the maximum WD. The proposed method, optimized for fluorescence expression-induced surgery, can be made available at clinical sites by mass producing them through semiconductor processes.
format Online
Article
Text
id pubmed-10670550
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-106705502023-11-20 Multi-Asymmetric Irradiation Method Using a Ring Array to Obtain an Emission-Capable LED Beam Power Effect to Observe Cancer Removal Status in a Surgical Microscope Lee, Seon Min Yoon, Kicheol Lee, Sangyun Ryu, Seung Yeob Kim, Kwang Gi Diagnostics (Basel) Article The light emitting diodes (LEDs) used in surgical fluorescence microscopes have weak power, to induce fluorescence emission. The LED induces fluorescence emission throughout a lesion due to its large beam width; however, the beam irradiation intensity is not uniform within the beam width, resulting in a fluorescence emission induction difference. To overcome this problem, this study proposes an asymmetric irradiation array for supplying power uniformly throughout the beam width of the LED and increasing the intensity of the LED. To increase the irradiation power of the LEDs, a multi-asymmetric irradiation method with a ring-type array structure was used. The LED consisted of eight rings, and the space between the LEDs, the placement position, and the placement angle were analyzed to devise an experimental method using 3D printing technology. To test the irradiation power of the LED, the working distance (WD) between the LED and target was 30 cm. The bias voltage of the LED for irradiating the light source was 5.0 V and the measured power was 4.63 mW. The brightness (lux) was 1153 lx. Consequently, the LED satisfied the fluorescence emission induction conditions. The diameter of the LED-irradiated area was 9.5 cm. Therefore, this LED could be used to observe fluorescent emission-guided lesions. This study maximized the advantages of LEDs with optimal conditions for fluorescence emission by increasing the beam width, irradiation area, and energy efficiency, using a small number of LEDs at the maximum WD. The proposed method, optimized for fluorescence expression-induced surgery, can be made available at clinical sites by mass producing them through semiconductor processes. MDPI 2023-11-20 /pmc/articles/PMC10670550/ /pubmed/37998618 http://dx.doi.org/10.3390/diagnostics13223482 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Lee, Seon Min
Yoon, Kicheol
Lee, Sangyun
Ryu, Seung Yeob
Kim, Kwang Gi
Multi-Asymmetric Irradiation Method Using a Ring Array to Obtain an Emission-Capable LED Beam Power Effect to Observe Cancer Removal Status in a Surgical Microscope
title Multi-Asymmetric Irradiation Method Using a Ring Array to Obtain an Emission-Capable LED Beam Power Effect to Observe Cancer Removal Status in a Surgical Microscope
title_full Multi-Asymmetric Irradiation Method Using a Ring Array to Obtain an Emission-Capable LED Beam Power Effect to Observe Cancer Removal Status in a Surgical Microscope
title_fullStr Multi-Asymmetric Irradiation Method Using a Ring Array to Obtain an Emission-Capable LED Beam Power Effect to Observe Cancer Removal Status in a Surgical Microscope
title_full_unstemmed Multi-Asymmetric Irradiation Method Using a Ring Array to Obtain an Emission-Capable LED Beam Power Effect to Observe Cancer Removal Status in a Surgical Microscope
title_short Multi-Asymmetric Irradiation Method Using a Ring Array to Obtain an Emission-Capable LED Beam Power Effect to Observe Cancer Removal Status in a Surgical Microscope
title_sort multi-asymmetric irradiation method using a ring array to obtain an emission-capable led beam power effect to observe cancer removal status in a surgical microscope
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10670550/
https://www.ncbi.nlm.nih.gov/pubmed/37998618
http://dx.doi.org/10.3390/diagnostics13223482
work_keys_str_mv AT leeseonmin multiasymmetricirradiationmethodusingaringarraytoobtainanemissioncapableledbeampowereffecttoobservecancerremovalstatusinasurgicalmicroscope
AT yoonkicheol multiasymmetricirradiationmethodusingaringarraytoobtainanemissioncapableledbeampowereffecttoobservecancerremovalstatusinasurgicalmicroscope
AT leesangyun multiasymmetricirradiationmethodusingaringarraytoobtainanemissioncapableledbeampowereffecttoobservecancerremovalstatusinasurgicalmicroscope
AT ryuseungyeob multiasymmetricirradiationmethodusingaringarraytoobtainanemissioncapableledbeampowereffecttoobservecancerremovalstatusinasurgicalmicroscope
AT kimkwanggi multiasymmetricirradiationmethodusingaringarraytoobtainanemissioncapableledbeampowereffecttoobservecancerremovalstatusinasurgicalmicroscope