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The Leptospermum scoparium (Mānuka)-Specific Nectar and Honey Compound 3,6,7-Trimethyllumazine (Lepteridine(TM)) That Inhibits Matrix Metalloproteinase 9 (MMP-9) Activity

3,6,7-trimethyllumazine (Lepteridine™) is a newly discovered natural pteridine derivative unique to Mānuka (Leptospermum scoparium) nectar and honey, with no previously reported biological activity. Pteridine derivative-based medicines, such as methotrexate, are used to treat auto-immune and inflamm...

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Detalles Bibliográficos
Autores principales: Lin, Bin, Nair, Smitha, Fellner, Daniel M. J., Nasef, Noha Ahmed, Singh, Harjinder, Negron, Leonardo, Goldstone, David C., Brimble, Margaret A., Gerrard, Juliet A., Domigan, Laura, Evans, Jackie C., Stephens, Jonathan M., Merry, Troy L., Loomes, Kerry M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10670905/
https://www.ncbi.nlm.nih.gov/pubmed/38002130
http://dx.doi.org/10.3390/foods12224072