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Dynamic Contrast-Enhanced Study in the mpMRI of the Prostate—Unnecessary or Underutilised? A Narrative Review

The aim of this review is to summarise recent scientific literature regarding the clinical use of DCE-MRI as a component of multiparametric resonance imaging of the prostate. This review presents the principles of DCE-MRI acquisition and analysis, the current role of DCE-MRI in clinical practice wit...

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Autores principales: Guljaš, Silva, Dupan Krivdić, Zdravka, Drežnjak Madunić, Maja, Šambić Penc, Mirela, Pavlović, Oliver, Krajina, Vinko, Pavoković, Deni, Šmit Takač, Petra, Štefančić, Marin, Salha, Tamer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10670922/
https://www.ncbi.nlm.nih.gov/pubmed/37998624
http://dx.doi.org/10.3390/diagnostics13223488
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author Guljaš, Silva
Dupan Krivdić, Zdravka
Drežnjak Madunić, Maja
Šambić Penc, Mirela
Pavlović, Oliver
Krajina, Vinko
Pavoković, Deni
Šmit Takač, Petra
Štefančić, Marin
Salha, Tamer
author_facet Guljaš, Silva
Dupan Krivdić, Zdravka
Drežnjak Madunić, Maja
Šambić Penc, Mirela
Pavlović, Oliver
Krajina, Vinko
Pavoković, Deni
Šmit Takač, Petra
Štefančić, Marin
Salha, Tamer
author_sort Guljaš, Silva
collection PubMed
description The aim of this review is to summarise recent scientific literature regarding the clinical use of DCE-MRI as a component of multiparametric resonance imaging of the prostate. This review presents the principles of DCE-MRI acquisition and analysis, the current role of DCE-MRI in clinical practice with special regard to its role in presently available categorisation systems, and an overview of the advantages and disadvantages of DCE-MRI described in the current literature. DCE-MRI is an important functional sequence that requires intravenous administration of a gadolinium-based contrast agent and gives information regarding the vascularity and capillary permeability of the lesion. Although numerous studies have confirmed that DCE-MRI has great potential in the diagnosis and monitoring of prostate cancer, its role is still inadequate in the PI-RADS categorisation. Moreover, there have been numerous scientific discussions about abandoning the intravenous application of gadolinium-based contrast as a routine part of MRI examination of the prostate. In this review, we summarised the recent literature on the advantages and disadvantages of DCE-MRI, focusing on an overview of currently available data on bpMRI and mpMRI, as well as on studies providing information on the potential better usability of DCE-MRI in improving the sensitivity and specificity of mpMRI examinations of the prostate.
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spelling pubmed-106709222023-11-20 Dynamic Contrast-Enhanced Study in the mpMRI of the Prostate—Unnecessary or Underutilised? A Narrative Review Guljaš, Silva Dupan Krivdić, Zdravka Drežnjak Madunić, Maja Šambić Penc, Mirela Pavlović, Oliver Krajina, Vinko Pavoković, Deni Šmit Takač, Petra Štefančić, Marin Salha, Tamer Diagnostics (Basel) Review The aim of this review is to summarise recent scientific literature regarding the clinical use of DCE-MRI as a component of multiparametric resonance imaging of the prostate. This review presents the principles of DCE-MRI acquisition and analysis, the current role of DCE-MRI in clinical practice with special regard to its role in presently available categorisation systems, and an overview of the advantages and disadvantages of DCE-MRI described in the current literature. DCE-MRI is an important functional sequence that requires intravenous administration of a gadolinium-based contrast agent and gives information regarding the vascularity and capillary permeability of the lesion. Although numerous studies have confirmed that DCE-MRI has great potential in the diagnosis and monitoring of prostate cancer, its role is still inadequate in the PI-RADS categorisation. Moreover, there have been numerous scientific discussions about abandoning the intravenous application of gadolinium-based contrast as a routine part of MRI examination of the prostate. In this review, we summarised the recent literature on the advantages and disadvantages of DCE-MRI, focusing on an overview of currently available data on bpMRI and mpMRI, as well as on studies providing information on the potential better usability of DCE-MRI in improving the sensitivity and specificity of mpMRI examinations of the prostate. MDPI 2023-11-20 /pmc/articles/PMC10670922/ /pubmed/37998624 http://dx.doi.org/10.3390/diagnostics13223488 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Guljaš, Silva
Dupan Krivdić, Zdravka
Drežnjak Madunić, Maja
Šambić Penc, Mirela
Pavlović, Oliver
Krajina, Vinko
Pavoković, Deni
Šmit Takač, Petra
Štefančić, Marin
Salha, Tamer
Dynamic Contrast-Enhanced Study in the mpMRI of the Prostate—Unnecessary or Underutilised? A Narrative Review
title Dynamic Contrast-Enhanced Study in the mpMRI of the Prostate—Unnecessary or Underutilised? A Narrative Review
title_full Dynamic Contrast-Enhanced Study in the mpMRI of the Prostate—Unnecessary or Underutilised? A Narrative Review
title_fullStr Dynamic Contrast-Enhanced Study in the mpMRI of the Prostate—Unnecessary or Underutilised? A Narrative Review
title_full_unstemmed Dynamic Contrast-Enhanced Study in the mpMRI of the Prostate—Unnecessary or Underutilised? A Narrative Review
title_short Dynamic Contrast-Enhanced Study in the mpMRI of the Prostate—Unnecessary or Underutilised? A Narrative Review
title_sort dynamic contrast-enhanced study in the mpmri of the prostate—unnecessary or underutilised? a narrative review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10670922/
https://www.ncbi.nlm.nih.gov/pubmed/37998624
http://dx.doi.org/10.3390/diagnostics13223488
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