Cargando…

Terpenes in Cannabis sativa Inhibit Capsaicin Responses in Rat DRG Neurons via Na(+)/K(+) ATPase Activation

Terpenes in Cannabis sativa exert analgesic effects, but the mechanisms are uncertain. We examined the effects of 10 terpenes on capsaicin responses in an established model of neuronal hypersensitivity. Adult rat DRG neurons cultured with neurotrophic factors NGF and GDNF were loaded with Fura2AM fo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Anand, Uma, Anand, Praveen, Sodergren, Mikael Hans
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10671062/ https://www.ncbi.nlm.nih.gov/pubmed/38003528 http://dx.doi.org/10.3390/ijms242216340

Ejemplares similares

The Endocannabinoid Analgesic Entourage Effect: Investigations in Cultured DRG Neurons
por: Anand, Uma, et al.
Publicado: (2022)

Sensitization of capsaicin and icilin responses in oxaliplatin treated adult rat DRG neurons
por: Anand, Uma, et al.
Publicado: (2010)

CBD Effects on TRPV1 Signaling Pathways in Cultured DRG Neurons
por: Anand, Uma, et al.
Publicado: (2020)

Dose-Related Inhibition of Capsaicin Responses by Cannabinoids CBG, CBD, THC and their Combination in Cultured Sensory Neurons
por: Anand, Uma, et al.
Publicado: (2021)

Terpene synthases from Cannabis sativa
por: Booth, Judith K., et al.
Publicado: (2017)

Secondary Terpenes in Cannabis sativa L.: Synthesis and Synergy
por: Chacon, Francisco T., et al.
Publicado: (2022)

Cannabis sativa terpenes are cannabimimetic and selectively enhance cannabinoid activity
por: LaVigne, Justin E., et al.
Publicado: (2021)

The Cannabis Terpenes
por: Sommano, Sarana Rose, et al.
Publicado: (2020)

Dietary capsaicin normalizes CGRP peptidergic DRG neurons in experimental diabetic peripheral neuropathy
por: Zhang, Xiao-Yi, et al.
Publicado: (2021)

Genomic characterization of the complete terpene synthase gene family from Cannabis sativa
por: Allen, Keith D., et al.
Publicado: (2019)

Regulation of Neuronal Na,K-ATPase by Extracellular Scaffolding Proteins
por: Liebmann, Thomas, et al.
Publicado: (2018)

Cannabinoids and Terpenes: How Production of Photo-Protectants Can Be Manipulated to Enhance Cannabis sativa L. Phytochemistry
por: Desaulniers Brousseau, Vincent, et al.
Publicado: (2021)

Extraction of Phenolic Compounds and Terpenes from Cannabis sativa L. By-Products: From Conventional to Intensified Processes
por: Isidore, Emilie, et al.
Publicado: (2021)

Cannabinoids, Phenolics, Terpenes and Alkaloids of Cannabis
por: Radwan, Mohamed M., et al.
Publicado: (2021)

Structural basis for inhibition of the AAA-ATPase Drg1 by diazaborine
por: Prattes, Michael, et al.
Publicado: (2021)

The preservation and augmentation of volatile terpenes in cannabis inflorescence
por: Bueno, Justin, et al.
Publicado: (2020)

A Comprehensive Phytochemical Analysis of Terpenes, Polyphenols and Cannabinoids, and Micromorphological Characterization of 9 Commercial Varieties of Cannabis sativa L.
por: Mazzara, Eugenia, et al.
Publicado: (2022)

Peripheral Inflammation Results in Increased Excitability of Capsaicin-Insensitive Nociceptive DRG Neurons Mediated by Upregulation of ASICs and Voltage-Gated Ion Channels
por: Duzhyy, Dmytro E., et al.
Publicado: (2021)

Mechanism of Na-K-ATPase Inhibition by PGE2 in Intestinal Epithelial Cells
por: Nepal, Niraj, et al.
Publicado: (2021)

Pretreatment with Zonisamide Mitigates Oxaliplatin-Induced Toxicity in Rat DRG Neurons and DRG Neuron–Schwann Cell Co-Cultures
por: Takaku, Shizuka, et al.
Publicado: (2022)

Unique Regulation of Na-K-ATPase during Growth and Maturation of Intestinal Epithelial Cells
por: Nepal, Niraj, et al.
Publicado: (2019)

β subunit affects Na(+) and K(+) affinities of Na(+)/K(+)-ATPase: Na(+) and K(+) affinities of a hybrid Na(+)/K(+)-ATPase composed of insect α and mammalian β subunits
por: Homareda, Haruo, et al.
Publicado: (2022)

Palytoxin-induced Effects on Partial Reactions of the Na,K-ATPase
por: Harmel, Nadine, et al.
Publicado: (2006)

Mycolactone-mediated neurite degeneration and functional effects in cultured human and rat DRG neurons: Mechanisms underlying hypoalgesia in Buruli ulcer
por: Anand, U, et al.
Publicado: (2016)

Na(+)/Ca(2+) exchange and Na(+)/K(+)-ATPase in the heart
por: Shattock, Michael J, et al.
Publicado: (2015)

Impacts of Different Light Spectra on CBD, CBDA and Terpene Concentrations in Relation to the Flower Positions of Different Cannabis Sativa L. Strains
por: Reichel, Philipp, et al.
Publicado: (2022)

Upregulation of T-type Ca(2+) channels in long-term diabetes determines increased excitability of a specific type of capsaicin-insensitive DRG neurons
por: Duzhyy, Dmytro E, et al.
Publicado: (2015)

C-peptide, Na(+),K(+)-ATPase, and Diabetes
por: Vague, P., et al.
Publicado: (2004)

Tuning of the Na,K-ATPase by the beta subunit
por: Hilbers, Florian, et al.
Publicado: (2016)

Transcriptional regulators of Na,K-ATPase subunits
por: Li, Zhiqin, et al.
Publicado: (2015)

Na(+), K(+)-ATPase Signaling and Bipolar Disorder
por: Lichtstein, David, et al.
Publicado: (2018)

Na/K-ATPase and Regulation of Sperm Function
por: Thundathil, Jacob C., et al.
Publicado: (2018)

The role of Na(+)‐K(+)‐ATPase in the epileptic brain
por: Sun, Jinyi, et al.
Publicado: (2022)

Structural dynamics of AAA + ATPase Drg1 and mechanism of benzo-diazaborine inhibition
por: Ma, Chengying, et al.
Publicado: (2022)

Paroxysmal extreme pain disorder M1627K mutation in human Na(v)1.7 renders DRG neurons hyperexcitable
por: Dib-Hajj, Sulayman D, et al.
Publicado: (2008)

Knockout of Slo2.2 enhances itch, abolishes K(Na) current, and increases action potential firing frequency in DRG neurons
por: Martinez-Espinosa, Pedro L, et al.
Publicado: (2015)

Lithium-induced inhibition of Na-K ATPase and Ca ATPase activities in rat brain synaptosome.
por: Cho, Y. W.
Publicado: (1995)

Extracellular Na(+) levels regulate formation and activity of the Na(X)/alpha1-Na(+)/K(+)-ATPase complex in neuronal cells
por: Berret, Emmanuelle, et al.
Publicado: (2014)

An interaction between PRRT2 and Na(+)/K(+) ATPase contributes to the control of neuronal excitability
por: Sterlini, Bruno, et al.
Publicado: (2021)

The parietal cell gastric H, K-ATPase also functions as the Na, K-ATPase and Ca-ATPase in altered states
por: Ray, Tushar
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_7vm2qtbp39cocbgi7q0r6q28ue