NXC736 Attenuates Radiation-Induced Lung Fibrosis via Regulating NLRP3/IL-1β Signaling Pathway

Radiation-induced lung fibrosis (RILF) is a common complication of radiotherapy in lung cancer. However, to date no effective treatment has been developed for this condition. NXC736 is a novel small-molecule compound that inhibits NLRP3, but its effect on RILF is unknown. NLRP3 activation is an impo...

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Detalles Bibliográficos
Autores principales: Kim, Sang Yeon, Park, Sunjoo, Cui, Ronglan, Lee, Hajeong, Choi, Hojung, Farh, Mohamed El-Agamy, Jo, Hai In, Lee, Jae Hee, Song, Hyo Jeong, Lee, Yoon-Jin, Lee, Yun-Sil, Lee, Bong Yong, Cho, Jaeho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10671169/
https://www.ncbi.nlm.nih.gov/pubmed/38003456
http://dx.doi.org/10.3390/ijms242216265

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10671169/
https://www.ncbi.nlm.nih.gov/pubmed/38003456
http://dx.doi.org/10.3390/ijms242216265

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