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PROTAC-Based Protein Degradation as a Promising Strategy for Targeted Therapy in Sarcomas

Sarcomas are heterogeneous bone and soft tissue cancers representing the second most common tumor type in children and adolescents. Histology and genetic profiling discovered more than 100 subtypes, which are characterized by peculiar molecular vulnerabilities. However, limited therapeutic options e...

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Detalles Bibliográficos
Autores principales: Mancarella, Caterina, Morrione, Andrea, Scotlandi, Katia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10671294/
https://www.ncbi.nlm.nih.gov/pubmed/38003535
http://dx.doi.org/10.3390/ijms242216346