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Can Activation of Acetylcholinesterase by β-Amyloid Peptide Decrease the Effectiveness of Cholinesterase Inhibitors?

A central event in the pathogenesis of Alzheimer’s disease (AD) is the accumulation of senile plaques composed of aggregated amyloid-β (Aβ) peptides. The main class of drugs currently used for the treatment of AD are the acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibitors. In thi...

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Detalles Bibliográficos
Autores principales:	Zueva, Irina V., Vasilieva, Elmira A., Gaynanova, Gulnara A., Moiseenko, Andrey V., Burtseva, Anna D., Boyko, Konstantin M., Zakharova, Lucia Ya., Petrov, Konstantin A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10671303/ https://www.ncbi.nlm.nih.gov/pubmed/38003588 http://dx.doi.org/10.3390/ijms242216395

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