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Frequency Evaluation of the Interleukin-6 −174G>C Polymorphism and Homeostatic Iron Regulator (HFE) Mutations as Disease Modifiers in Patients Affected by Systemic Lupus Erythematosus and Rheumatoid Arthritis

Autoimmune diseases are generally characterized by a multifactorial etiology and are often associated with a genetic predisposition. Both iron metabolism and the inflammatory cytokine system have been shown to play a pivotal role in the dysregulation of the immune response in many different autoimmu...

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Detalles Bibliográficos
Autores principales: Carini, Mattia, Fredi, Micaela, Cavazzana, Ilaria, Bresciani, Roberto, Ferrari, Fabiana, Monti, Eugenio, Franceschini, Franco, Biasiotto, Giorgio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10671518/
https://www.ncbi.nlm.nih.gov/pubmed/38003490
http://dx.doi.org/10.3390/ijms242216300

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