Improved Reversion of Calcifications in Porcine Aortic Heart Valves Using Elastin-Targeted Nanoparticles

Calcified aortic valve disease in its final stage leads to aortic valve stenosis, limiting cardiac function. To date, surgical intervention is the only option for treating calcific aortic valve stenosis. This study combined controlled drug delivery by nanoparticles (NPs) and active targeting by anti...

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Detalles Bibliográficos
Autores principales: Feldmann, Anja, Nitschke, Yvonne, Linß, Franziska, Mulac, Dennis, Stücker, Sina, Bertrand, Jessica, Buers, Insa, Langer, Klaus, Rutsch, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10671589/
https://www.ncbi.nlm.nih.gov/pubmed/38003660
http://dx.doi.org/10.3390/ijms242216471

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