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Experimental Study: Interleukin-31 Augments Morphine-Induced Antinociceptive Activity and Suppress Tolerance Development in Mice

Morphine-induced antinociception is partially reduced in interleukin-31 (IL-31) receptor A (IL-31RA)-deficient mice, indicating that IL-31RA is crucial for morphine-induced peripheral antinociception. Herein, we examined the combined effects of IL-31 and morphine on the antinociceptive activity and...

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Detalles Bibliográficos
Autores principales: Arai, Iwao, Tsuji, Minoru, Saito, Saburo, Takeda, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10671644/
https://www.ncbi.nlm.nih.gov/pubmed/38003738
http://dx.doi.org/10.3390/ijms242216548

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