Increase in hnRNPA1 Expression Suffices to Kill Motor Neurons in Transgenic Rats

A dominant mutation in hnRNPA1 causes amyotrophic lateral sclerosis (ALS), but it is not known whether this mutation leads to motor neuron death through increased or decreased function. To elucidate the relationship between pathogenic hnRNPA1 mutation and its native function, we created novel transg...

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Detalles Bibliográficos
Autores principales: Huang, Bo, Liu, Xionghao, Zhang, Tingting, Wu, Qinxue, Huang, Cao, Xia, Xu-Gang, Zhou, Hongxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10671660/
https://www.ncbi.nlm.nih.gov/pubmed/38003404
http://dx.doi.org/10.3390/ijms242216214

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10671660/
https://www.ncbi.nlm.nih.gov/pubmed/38003404
http://dx.doi.org/10.3390/ijms242216214

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