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Increase in hnRNPA1 Expression Suffices to Kill Motor Neurons in Transgenic Rats
A dominant mutation in hnRNPA1 causes amyotrophic lateral sclerosis (ALS), but it is not known whether this mutation leads to motor neuron death through increased or decreased function. To elucidate the relationship between pathogenic hnRNPA1 mutation and its native function, we created novel transg...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10671660/ https://www.ncbi.nlm.nih.gov/pubmed/38003404 http://dx.doi.org/10.3390/ijms242216214 |