Cargando…

Uncovering the Genetic and Molecular Features of Huntington’s Disease in Northern Colombia

Huntington’s disease (HD) is a genetic disorder caused by a CAG trinucleotide expansion in the huntingtin (HTT) gene. Juan de Acosta, Atlántico, a city located on the Caribbean coast of Colombia, is home to the world’s second-largest HD pedigree. Here, we include 291 descendants of this pedigree wit...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ahmad, Mostapha, Ríos-Anillo, Margarita R., Acosta-López, Johan E., Cervantes-Henríquez, Martha L., Martínez-Banfi, Martha, Pineda-Alhucema, Wilmar, Puentes-Rozo, Pedro, Sánchez-Barros, Cristian, Pinzón, Andrés, Patel, Hardip R., Vélez, Jorge I., Villarreal-Camacho, José Luis, Pineda, David A., Arcos-Burgos, Mauricio, Sánchez-Rojas, Manuel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10671691/ https://www.ncbi.nlm.nih.gov/pubmed/38003344 http://dx.doi.org/10.3390/ijms242216154

Ejemplares similares

ADGRL3, FGF1 and DRD4: Linkage and Association with Working Memory and Perceptual Organization Candidate Endophenotypes in ADHD
por: Cervantes-Henriquez, Martha L., et al.
Publicado: (2021)

Impulsive and Omission Errors: Potential Temporal Processing Endophenotypes in ADHD †
por: Acosta-López, Johan E., et al.
Publicado: (2021)

Genetic Variation Underpinning ADHD Risk in a Caribbean Community
por: Puentes-Rozo, Pedro J., et al.
Publicado: (2019)

ADGRL3 (LPHN3) variants predict substance use disorder
por: Arcos-Burgos, Mauricio, et al.
Publicado: (2019)

Characterization of neuropsychiatric symptoms in a group of individuals with manifest or pre-motor Huntington’s disease in Medellín, Colombia
por: Vasquez, D., et al.
Publicado: (2022)

Fusarium spp. associated with Chenopodium quinoa crops in Colombia
por: Fonseca-Guerra, Ingrid Rocio, et al.
Publicado: (2022)

Anthropophilic Anopheles species composition and malaria in Tierradentro, Córdoba, Colombia
por: Schiemann, David Joachim, et al.
Publicado: (2014)

Characterization of Alternaria alternata and Alternaria scrophulariae Brown Spot in Colombian quinoa (Chenopodium quinoa)
por: Fonseca-Guerra, Ingrid Rocío, et al.
Publicado: (2023)

La familia en Colombia
por: Gutiérrez de Pineda, Virginia
Publicado: (1963)

La familia en Colombia : estudio antropológico
por: Gutiérrez de Pineda, Virginia
Publicado: (1962)

Utility of a Short Neuropsychological Protocol for Detecting HIV-Associated Neurocognitive Disorders in Patients with Asymptomatic HIV-1 Infection
por: Martinez-Banfi, Martha, et al.
Publicado: (2021)

Updated list of the mosquitoes of Colombia (Diptera: Culicidae)
por: Rozo-Lopez, Paula, et al.
Publicado: (2015)

Assessment of Potential Health Risks Associated with the Intake of Heavy Metals in Fish Harvested from the Largest Estuary in Colombia
por: Pinzón-Bedoya, Carlos H., et al.
Publicado: (2020)

La medicina popular en Colombia: razones de su arraigo
por: Gutiérrez de Pineda, Virginia
Publicado: (1961)

Costs of sickness absence in a service company in Colombia: case analysis by gender and occupation
por: Palencia-Sánchez, Francisco, et al.
Publicado: (2023)

Estimation of the Need for Radiation Therapy Services According to the Incidence of Cancer in Colombia to 2035
por: Gamboa, Oscar, et al.
Publicado: (2021)

Case Series Study of Melioidosis, Colombia
por: Rodríguez, José Y., et al.
Publicado: (2019)

Mutations in sphingolipid metabolism genes are associated with ADHD
por: Henriquez-Henriquez, Marcela, et al.
Publicado: (2020)

CNVs in the 22q11.2 Chromosomal Region Should Be an Early Suspect in Infants with Congenital Cardiac Disease
por: Pineda, Tatiana, et al.
Publicado: (2021)

Chemical, structural, and thermal characterization of starches from four yellow Arracacha (Arracacia xanthorriza) roots produced in Colombia
por: Pinzon, Magda I., et al.
Publicado: (2020)

Successful Aging in Colombia: The Role of Disease
por: Curcio, Carmen-Lucia, et al.
Publicado: (2018)

A Mutation in DAOA Modifies the Age of Onset in PSEN1 E280A Alzheimer's Disease
por: Vélez, Jorge I., et al.
Publicado: (2016)

The Cost of Lost Productivity Due to Premature Chagas Disease-Related Mortality: Lessons from Colombia (2010–2017)
por: Olivera, Mario J., et al.
Publicado: (2021)

Multidrug-Resistant Mycobacterium tuberculosis, Southwestern Colombia
por: Ferro, Beatriz E., et al.
Publicado: (2011)

A new species of Leucostethus (Anura, Dendrobatidae) from Gorgona Island, Colombia
por: Grant, Taran, et al.
Publicado: (2021)

Implementation of a Postfracture Care Program in a Private Hospital in Colombia
por: Sánchez, M. A., et al.
Publicado: (2020)

Connectivity mapping uncovers small molecules that modulate neurodegeneration in Huntington’s disease models
por: Smalley, Joshua L., et al.
Publicado: (2015)

Characterization of Eyeball Loss in Four Cities of Colombia
por: Moreno-Caviedes, F. Hernán, et al.
Publicado: (2017)

New records of Sabethini (Diptera: Culicidae) from Colombia
por: Naranjo-Díaz, Nelson, et al.
Publicado: (2022)

Interleukin-6 deficiency exacerbates Huntington’s disease model phenotypes
por: Wertz, Mary H., et al.
Publicado: (2020)

Genetic parameters in traits of productive importance in lines of Bombyx mori L.
por: Zambrano‐Gonzalez, Giselle, et al.
Publicado: (2021)

Fragmentation of Care and Its Association With Survival and Costs for Patients With Breast Cancer in Colombia
por: Gamboa, Óscar, et al.
Publicado: (2023)

Active and latent tuberculosis among inmates in La Esperanza prison in Guaduas, Colombia
por: Guerra, Julio, et al.
Publicado: (2019)

Uncovering the Effect of Al Addition on the Hydrogen Storage Properties of the Ternary TiVNb Alloy
por: Pineda-Romero, Nayely, et al.
Publicado: (2022)

Remote Automated Peritoneal Dialysis Management in Colombia
por: Bunch, Alfonso, et al.
Publicado: (2019)

First report of environmental isolation of Cryptococcus and Cryptococcus-like yeasts from Boyacá, Colombia
por: Serna-Espinosa, Briggith-Nathalia, et al.
Publicado: (2023)

Phenotypic Characterization and Whole Genome Analysis of a Strong Biofilm-Forming Staphylococcus aureus Strain Associated With Subclinical Bovine Mastitis in Colombia
por: Torres, Giovanny, et al.
Publicado: (2020)

Targeting Neuroplasticity, Cardiovascular, and Cognitive-Associated Genomic Variants in Familial Alzheimer’s Disease
por: Vélez, Jorge I., et al.
Publicado: (2018)

Genetic and pharmacological inhibition of calcineurin corrects the BDNF transport defect in Huntington's disease
por: Pineda, Jose R, et al.
Publicado: (2009)

Population Status of Iodine and Its Potential Effects on Thyroid Function and Autoimmunity in Southwestern Colombia
por: Vargas-Uricoechea, Hernando, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_9omkdh8g014kt4i8m7t5dlogis