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Activation of Purine Biosynthesis Suppresses the Sensitivity of E. coli gmhA Mutant to Antibiotics

Inactivation of enzymes responsible for biosynthesis of the cell wall component of ADP-glycero-manno-heptose causes the development of oxidative stress and sensitivity of bacteria to antibiotics of a hydrophobic nature. The metabolic precursor of ADP-heptose is sedoheptulose-7-phosphate (S7P), an in...

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Detalles Bibliográficos
Autores principales:	Seregina, Tatiana A., Petrushanko, Irina Yu., Zaripov, Pavel I., Shakulov, Rustem S., A. Sklyarova, Svetlana, Mitkevich, Vladimir A., Makarov, Alexander A., Mironov, Alexander S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10671730/ https://www.ncbi.nlm.nih.gov/pubmed/38003258 http://dx.doi.org/10.3390/ijms242216070

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