A Strategy Utilizing Protein–Protein Interaction Hubs for the Treatment of Cancer Diseases

We describe a strategy for the development of a rational approach of neoplastic disease therapy based on the demonstration that scale-free networks are susceptible to specific attacks directed against its connective hubs. This strategy involves the (i) selection of up-regulated hubs of connectivity...

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Detalles Bibliográficos
Autores principales: Carels, Nicolas, Sgariglia, Domenico, Junior, Marcos Guilherme Vieira, Lima, Carlyle Ribeiro, Carneiro, Flávia Raquel Gonçalves, da Silva, Gilberto Ferreira, da Silva, Fabricio Alves Barbosa, Scardini, Rafaela, Tuszynski, Jack Adam, de Andrade, Cecilia Vianna, Monteiro, Ana Carolina, Martins, Marcel Guimarães, da Silva, Talita Goulart, Ferraz, Helen, Finotelli, Priscilla Vanessa, Balbino, Tiago Albertini, Pinto, José Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10671768/
https://www.ncbi.nlm.nih.gov/pubmed/38003288
http://dx.doi.org/10.3390/ijms242216098

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