Beta-Hydroxyisovaleryl-Shikonin Eradicates Epithelial Cell Adhesion Molecule-Positive Liver Cancer Stem Cells by Suppressing dUTP Pyrophosphatase Expression

Cancer stem cells (CSCs) play an essential role in tumorigenesis, chemoresistance, and metastasis. Previously, we demonstrated that the development of hepatocellular carcinoma (HCC) is dictated by a subset of epithelial cell adhesion molecule-positive (EpCAM+) liver CSCs with the activation of Wnt s...

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Detalles Bibliográficos
Autores principales: Asahina, Yoshiro, Takatori, Hajime, Nio, Kouki, Okada, Hikari, Hayashi, Takehiro, Hayashi, Tomoyuki, Hashiba, Tomomi, Suda, Tsuyoshi, Nishitani, Masaki, Sugimoto, Saiho, Honda, Masao, Kaneko, Shuichi, Yamashita, Taro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10671815/
https://www.ncbi.nlm.nih.gov/pubmed/38003473
http://dx.doi.org/10.3390/ijms242216283

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10671815/
https://www.ncbi.nlm.nih.gov/pubmed/38003473
http://dx.doi.org/10.3390/ijms242216283

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