Cargando…
Secondary Metabolites from Fungi Microsphaeropsis spp.: Chemistry and Bioactivities
Microsphaeropsis, taxonomically classified within the kingdom fungi, phylum Ascomycota, subphylum Deuteromycotina, class Coelomycetes, order Sphaeropsidales, and family Sphaeropsidaceae, exhibit a ubiquitous distribution across various geographical regions. These fungi are known for their production...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10671944/ https://www.ncbi.nlm.nih.gov/pubmed/37998898 http://dx.doi.org/10.3390/jof9111093 |
_version_ | 1785140275017940992 |
---|---|
author | Song, Guodong Zhang, Zhibin Niu, Xuenan Zhu, Du |
author_facet | Song, Guodong Zhang, Zhibin Niu, Xuenan Zhu, Du |
author_sort | Song, Guodong |
collection | PubMed |
description | Microsphaeropsis, taxonomically classified within the kingdom fungi, phylum Ascomycota, subphylum Deuteromycotina, class Coelomycetes, order Sphaeropsidales, and family Sphaeropsidaceae, exhibit a ubiquitous distribution across various geographical regions. These fungi are known for their production of secondary metabolites, characterized by both structural novelty and potent biological activity. Consequently, they represent a significant reservoir for the advancement of novel pharmaceuticals. In this paper, a systematic review was present, marking the analysis of secondary metabolites synthesized by Microsphaeropsis reported between 1980 and 2023. A total of 112 compounds, comprising polyketones, macrolides, terpenoids, and nitrogen-containing compounds, were reported from Microsphaeropsis. Remarkably, among these compounds, 49 are novel discoveries, marking a significant contribution to the field. A concise summary of their diverse biological activities was provided, including antibacterial, antitumor, and antiviral properties and other bioactivities. This analysis stands as a valuable reference, poised to guide further investigations into the active natural products derived from Microsphaeropsis and their potential contributions to the development of medicinal resources. |
format | Online Article Text |
id | pubmed-10671944 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-106719442023-11-09 Secondary Metabolites from Fungi Microsphaeropsis spp.: Chemistry and Bioactivities Song, Guodong Zhang, Zhibin Niu, Xuenan Zhu, Du J Fungi (Basel) Review Microsphaeropsis, taxonomically classified within the kingdom fungi, phylum Ascomycota, subphylum Deuteromycotina, class Coelomycetes, order Sphaeropsidales, and family Sphaeropsidaceae, exhibit a ubiquitous distribution across various geographical regions. These fungi are known for their production of secondary metabolites, characterized by both structural novelty and potent biological activity. Consequently, they represent a significant reservoir for the advancement of novel pharmaceuticals. In this paper, a systematic review was present, marking the analysis of secondary metabolites synthesized by Microsphaeropsis reported between 1980 and 2023. A total of 112 compounds, comprising polyketones, macrolides, terpenoids, and nitrogen-containing compounds, were reported from Microsphaeropsis. Remarkably, among these compounds, 49 are novel discoveries, marking a significant contribution to the field. A concise summary of their diverse biological activities was provided, including antibacterial, antitumor, and antiviral properties and other bioactivities. This analysis stands as a valuable reference, poised to guide further investigations into the active natural products derived from Microsphaeropsis and their potential contributions to the development of medicinal resources. MDPI 2023-11-09 /pmc/articles/PMC10671944/ /pubmed/37998898 http://dx.doi.org/10.3390/jof9111093 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Song, Guodong Zhang, Zhibin Niu, Xuenan Zhu, Du Secondary Metabolites from Fungi Microsphaeropsis spp.: Chemistry and Bioactivities |
title | Secondary Metabolites from Fungi Microsphaeropsis spp.: Chemistry and Bioactivities |
title_full | Secondary Metabolites from Fungi Microsphaeropsis spp.: Chemistry and Bioactivities |
title_fullStr | Secondary Metabolites from Fungi Microsphaeropsis spp.: Chemistry and Bioactivities |
title_full_unstemmed | Secondary Metabolites from Fungi Microsphaeropsis spp.: Chemistry and Bioactivities |
title_short | Secondary Metabolites from Fungi Microsphaeropsis spp.: Chemistry and Bioactivities |
title_sort | secondary metabolites from fungi microsphaeropsis spp.: chemistry and bioactivities |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10671944/ https://www.ncbi.nlm.nih.gov/pubmed/37998898 http://dx.doi.org/10.3390/jof9111093 |
work_keys_str_mv | AT songguodong secondarymetabolitesfromfungimicrosphaeropsissppchemistryandbioactivities AT zhangzhibin secondarymetabolitesfromfungimicrosphaeropsissppchemistryandbioactivities AT niuxuenan secondarymetabolitesfromfungimicrosphaeropsissppchemistryandbioactivities AT zhudu secondarymetabolitesfromfungimicrosphaeropsissppchemistryandbioactivities |