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Cryosurgery for Basal Cell Skin Cancer of the Head: 15 Years of Experience

The clinical relevance of head and neck (H&N) tumors is related to the potential disfiguration of anatomical structures (by the tumor or surgical intervention), defining patients’ individual features and emotional expression, loss or restraint of vital structures functions, and untoward socio-ec...

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Autores principales: Pustinsky, Ilya, Dvornikov, Anton, Kiva, Ekaterina, Chulkova, Svetlana, Egorova, Angelina, Gladilina, Irina, Peterson, Sergey, Lepkova, Nataly, Grishchenko, Natalya, Galaeva, Zamira, Baisova, Aigul, Kalinin, Sergey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10671957/
https://www.ncbi.nlm.nih.gov/pubmed/38004371
http://dx.doi.org/10.3390/life13112231
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author Pustinsky, Ilya
Dvornikov, Anton
Kiva, Ekaterina
Chulkova, Svetlana
Egorova, Angelina
Gladilina, Irina
Peterson, Sergey
Lepkova, Nataly
Grishchenko, Natalya
Galaeva, Zamira
Baisova, Aigul
Kalinin, Sergey
author_facet Pustinsky, Ilya
Dvornikov, Anton
Kiva, Ekaterina
Chulkova, Svetlana
Egorova, Angelina
Gladilina, Irina
Peterson, Sergey
Lepkova, Nataly
Grishchenko, Natalya
Galaeva, Zamira
Baisova, Aigul
Kalinin, Sergey
author_sort Pustinsky, Ilya
collection PubMed
description The clinical relevance of head and neck (H&N) tumors is related to the potential disfiguration of anatomical structures (by the tumor or surgical intervention), defining patients’ individual features and emotional expression, loss or restraint of vital structures functions, and untoward socio-economic sequelae. This study is aimed to improve clinical outcomes of cryosurgery in patients with H&N basal cell skin cancer by refining the indications for cryosurgical treatment. In this study, cryosurgery was used in 234 patients with different stages of cutaneous basal cell carcinoma (BCC) of the head, including 101 patients with T1 tumors, 86—with T2, 5—T3, and 42 patients with tumors relapsing after failure of preceding various treatment modalities. Post-cryosurgery recurrence rate in patients with stage I BCC was 2.7%, with stage II tumors—5.6% and 34.9%—in patients with recurred tumors. Re-recurrence after cryoablation of recurrent tumors correlated with the tumor baseline size. The best aesthetic and long-term clinical results were documented in patients with lesions <1 cm in size with clear boundaries. Thus, cryosurgery is the method of choice for the majority of stage I basal cell carcinomas of the head. For patients with advanced and recurrent skin cancer, cryosurgery is relevant in rare cases selected according to refined indications.
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spelling pubmed-106719572023-11-20 Cryosurgery for Basal Cell Skin Cancer of the Head: 15 Years of Experience Pustinsky, Ilya Dvornikov, Anton Kiva, Ekaterina Chulkova, Svetlana Egorova, Angelina Gladilina, Irina Peterson, Sergey Lepkova, Nataly Grishchenko, Natalya Galaeva, Zamira Baisova, Aigul Kalinin, Sergey Life (Basel) Article The clinical relevance of head and neck (H&N) tumors is related to the potential disfiguration of anatomical structures (by the tumor or surgical intervention), defining patients’ individual features and emotional expression, loss or restraint of vital structures functions, and untoward socio-economic sequelae. This study is aimed to improve clinical outcomes of cryosurgery in patients with H&N basal cell skin cancer by refining the indications for cryosurgical treatment. In this study, cryosurgery was used in 234 patients with different stages of cutaneous basal cell carcinoma (BCC) of the head, including 101 patients with T1 tumors, 86—with T2, 5—T3, and 42 patients with tumors relapsing after failure of preceding various treatment modalities. Post-cryosurgery recurrence rate in patients with stage I BCC was 2.7%, with stage II tumors—5.6% and 34.9%—in patients with recurred tumors. Re-recurrence after cryoablation of recurrent tumors correlated with the tumor baseline size. The best aesthetic and long-term clinical results were documented in patients with lesions <1 cm in size with clear boundaries. Thus, cryosurgery is the method of choice for the majority of stage I basal cell carcinomas of the head. For patients with advanced and recurrent skin cancer, cryosurgery is relevant in rare cases selected according to refined indications. MDPI 2023-11-20 /pmc/articles/PMC10671957/ /pubmed/38004371 http://dx.doi.org/10.3390/life13112231 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Pustinsky, Ilya
Dvornikov, Anton
Kiva, Ekaterina
Chulkova, Svetlana
Egorova, Angelina
Gladilina, Irina
Peterson, Sergey
Lepkova, Nataly
Grishchenko, Natalya
Galaeva, Zamira
Baisova, Aigul
Kalinin, Sergey
Cryosurgery for Basal Cell Skin Cancer of the Head: 15 Years of Experience
title Cryosurgery for Basal Cell Skin Cancer of the Head: 15 Years of Experience
title_full Cryosurgery for Basal Cell Skin Cancer of the Head: 15 Years of Experience
title_fullStr Cryosurgery for Basal Cell Skin Cancer of the Head: 15 Years of Experience
title_full_unstemmed Cryosurgery for Basal Cell Skin Cancer of the Head: 15 Years of Experience
title_short Cryosurgery for Basal Cell Skin Cancer of the Head: 15 Years of Experience
title_sort cryosurgery for basal cell skin cancer of the head: 15 years of experience
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10671957/
https://www.ncbi.nlm.nih.gov/pubmed/38004371
http://dx.doi.org/10.3390/life13112231
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