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Cryosurgery for Basal Cell Skin Cancer of the Head: 15 Years of Experience
The clinical relevance of head and neck (H&N) tumors is related to the potential disfiguration of anatomical structures (by the tumor or surgical intervention), defining patients’ individual features and emotional expression, loss or restraint of vital structures functions, and untoward socio-ec...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10671957/ https://www.ncbi.nlm.nih.gov/pubmed/38004371 http://dx.doi.org/10.3390/life13112231 |
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author | Pustinsky, Ilya Dvornikov, Anton Kiva, Ekaterina Chulkova, Svetlana Egorova, Angelina Gladilina, Irina Peterson, Sergey Lepkova, Nataly Grishchenko, Natalya Galaeva, Zamira Baisova, Aigul Kalinin, Sergey |
author_facet | Pustinsky, Ilya Dvornikov, Anton Kiva, Ekaterina Chulkova, Svetlana Egorova, Angelina Gladilina, Irina Peterson, Sergey Lepkova, Nataly Grishchenko, Natalya Galaeva, Zamira Baisova, Aigul Kalinin, Sergey |
author_sort | Pustinsky, Ilya |
collection | PubMed |
description | The clinical relevance of head and neck (H&N) tumors is related to the potential disfiguration of anatomical structures (by the tumor or surgical intervention), defining patients’ individual features and emotional expression, loss or restraint of vital structures functions, and untoward socio-economic sequelae. This study is aimed to improve clinical outcomes of cryosurgery in patients with H&N basal cell skin cancer by refining the indications for cryosurgical treatment. In this study, cryosurgery was used in 234 patients with different stages of cutaneous basal cell carcinoma (BCC) of the head, including 101 patients with T1 tumors, 86—with T2, 5—T3, and 42 patients with tumors relapsing after failure of preceding various treatment modalities. Post-cryosurgery recurrence rate in patients with stage I BCC was 2.7%, with stage II tumors—5.6% and 34.9%—in patients with recurred tumors. Re-recurrence after cryoablation of recurrent tumors correlated with the tumor baseline size. The best aesthetic and long-term clinical results were documented in patients with lesions <1 cm in size with clear boundaries. Thus, cryosurgery is the method of choice for the majority of stage I basal cell carcinomas of the head. For patients with advanced and recurrent skin cancer, cryosurgery is relevant in rare cases selected according to refined indications. |
format | Online Article Text |
id | pubmed-10671957 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-106719572023-11-20 Cryosurgery for Basal Cell Skin Cancer of the Head: 15 Years of Experience Pustinsky, Ilya Dvornikov, Anton Kiva, Ekaterina Chulkova, Svetlana Egorova, Angelina Gladilina, Irina Peterson, Sergey Lepkova, Nataly Grishchenko, Natalya Galaeva, Zamira Baisova, Aigul Kalinin, Sergey Life (Basel) Article The clinical relevance of head and neck (H&N) tumors is related to the potential disfiguration of anatomical structures (by the tumor or surgical intervention), defining patients’ individual features and emotional expression, loss or restraint of vital structures functions, and untoward socio-economic sequelae. This study is aimed to improve clinical outcomes of cryosurgery in patients with H&N basal cell skin cancer by refining the indications for cryosurgical treatment. In this study, cryosurgery was used in 234 patients with different stages of cutaneous basal cell carcinoma (BCC) of the head, including 101 patients with T1 tumors, 86—with T2, 5—T3, and 42 patients with tumors relapsing after failure of preceding various treatment modalities. Post-cryosurgery recurrence rate in patients with stage I BCC was 2.7%, with stage II tumors—5.6% and 34.9%—in patients with recurred tumors. Re-recurrence after cryoablation of recurrent tumors correlated with the tumor baseline size. The best aesthetic and long-term clinical results were documented in patients with lesions <1 cm in size with clear boundaries. Thus, cryosurgery is the method of choice for the majority of stage I basal cell carcinomas of the head. For patients with advanced and recurrent skin cancer, cryosurgery is relevant in rare cases selected according to refined indications. MDPI 2023-11-20 /pmc/articles/PMC10671957/ /pubmed/38004371 http://dx.doi.org/10.3390/life13112231 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Pustinsky, Ilya Dvornikov, Anton Kiva, Ekaterina Chulkova, Svetlana Egorova, Angelina Gladilina, Irina Peterson, Sergey Lepkova, Nataly Grishchenko, Natalya Galaeva, Zamira Baisova, Aigul Kalinin, Sergey Cryosurgery for Basal Cell Skin Cancer of the Head: 15 Years of Experience |
title | Cryosurgery for Basal Cell Skin Cancer of the Head: 15 Years of Experience |
title_full | Cryosurgery for Basal Cell Skin Cancer of the Head: 15 Years of Experience |
title_fullStr | Cryosurgery for Basal Cell Skin Cancer of the Head: 15 Years of Experience |
title_full_unstemmed | Cryosurgery for Basal Cell Skin Cancer of the Head: 15 Years of Experience |
title_short | Cryosurgery for Basal Cell Skin Cancer of the Head: 15 Years of Experience |
title_sort | cryosurgery for basal cell skin cancer of the head: 15 years of experience |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10671957/ https://www.ncbi.nlm.nih.gov/pubmed/38004371 http://dx.doi.org/10.3390/life13112231 |
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