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Endo Belly: What Is It and Why Does It Happen?—A Narrative Review

Endometriosis is a chronic inflammatory disease where endometrial-like lesions settle outside the uterus, resulting in extensive inflammatory reactions. It is a complex disease that presents with a range of symptoms, with pain and infertility being the most common. Along with severe dysmenorrhea, cy...

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Autores principales: Velho, Renata Voltolini, Werner, Franziska, Mechsner, Sylvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10671958/
https://www.ncbi.nlm.nih.gov/pubmed/38002788
http://dx.doi.org/10.3390/jcm12227176
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author Velho, Renata Voltolini
Werner, Franziska
Mechsner, Sylvia
author_facet Velho, Renata Voltolini
Werner, Franziska
Mechsner, Sylvia
author_sort Velho, Renata Voltolini
collection PubMed
description Endometriosis is a chronic inflammatory disease where endometrial-like lesions settle outside the uterus, resulting in extensive inflammatory reactions. It is a complex disease that presents with a range of symptoms, with pain and infertility being the most common. Along with severe dysmenorrhea, cyclic and acyclic lower abdominal pain, cyclic dysuria and dyschezia, dyspareunia, and infertility, there are also nonspecific complaints that can cause confusion and make endometriosis the chameleon among gynecological diseases. These symptoms include unspecific intestinal complaints, cyclic diarrhea, but also constipation, nausea, vomiting, and stomach complaints. It appears that in addition to general bowel symptoms, there are also specific symptoms related to endometriosis such as cyclic bloating of the abdomen, known as endo belly. During the second half of the menstrual cycle leading up to menstruation, the abdomen becomes increasingly bloated causing discomfort and pain due to elevated sensitivity of the intestinal wall. Patients with endometriosis exhibit a reduced stretch pain threshold of the intestinal wall. Here, we review the endo belly, for the first time, pathophysiology and the influence of other diseases (such as irritable bowel syndrome—IBS), microbiome, hormonal levels, inflammation, and diet on the presentation of this condition.
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spelling pubmed-106719582023-11-19 Endo Belly: What Is It and Why Does It Happen?—A Narrative Review Velho, Renata Voltolini Werner, Franziska Mechsner, Sylvia J Clin Med Review Endometriosis is a chronic inflammatory disease where endometrial-like lesions settle outside the uterus, resulting in extensive inflammatory reactions. It is a complex disease that presents with a range of symptoms, with pain and infertility being the most common. Along with severe dysmenorrhea, cyclic and acyclic lower abdominal pain, cyclic dysuria and dyschezia, dyspareunia, and infertility, there are also nonspecific complaints that can cause confusion and make endometriosis the chameleon among gynecological diseases. These symptoms include unspecific intestinal complaints, cyclic diarrhea, but also constipation, nausea, vomiting, and stomach complaints. It appears that in addition to general bowel symptoms, there are also specific symptoms related to endometriosis such as cyclic bloating of the abdomen, known as endo belly. During the second half of the menstrual cycle leading up to menstruation, the abdomen becomes increasingly bloated causing discomfort and pain due to elevated sensitivity of the intestinal wall. Patients with endometriosis exhibit a reduced stretch pain threshold of the intestinal wall. Here, we review the endo belly, for the first time, pathophysiology and the influence of other diseases (such as irritable bowel syndrome—IBS), microbiome, hormonal levels, inflammation, and diet on the presentation of this condition. MDPI 2023-11-19 /pmc/articles/PMC10671958/ /pubmed/38002788 http://dx.doi.org/10.3390/jcm12227176 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Velho, Renata Voltolini
Werner, Franziska
Mechsner, Sylvia
Endo Belly: What Is It and Why Does It Happen?—A Narrative Review
title Endo Belly: What Is It and Why Does It Happen?—A Narrative Review
title_full Endo Belly: What Is It and Why Does It Happen?—A Narrative Review
title_fullStr Endo Belly: What Is It and Why Does It Happen?—A Narrative Review
title_full_unstemmed Endo Belly: What Is It and Why Does It Happen?—A Narrative Review
title_short Endo Belly: What Is It and Why Does It Happen?—A Narrative Review
title_sort endo belly: what is it and why does it happen?—a narrative review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10671958/
https://www.ncbi.nlm.nih.gov/pubmed/38002788
http://dx.doi.org/10.3390/jcm12227176
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