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Endo Belly: What Is It and Why Does It Happen?—A Narrative Review
Endometriosis is a chronic inflammatory disease where endometrial-like lesions settle outside the uterus, resulting in extensive inflammatory reactions. It is a complex disease that presents with a range of symptoms, with pain and infertility being the most common. Along with severe dysmenorrhea, cy...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10671958/ https://www.ncbi.nlm.nih.gov/pubmed/38002788 http://dx.doi.org/10.3390/jcm12227176 |
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author | Velho, Renata Voltolini Werner, Franziska Mechsner, Sylvia |
author_facet | Velho, Renata Voltolini Werner, Franziska Mechsner, Sylvia |
author_sort | Velho, Renata Voltolini |
collection | PubMed |
description | Endometriosis is a chronic inflammatory disease where endometrial-like lesions settle outside the uterus, resulting in extensive inflammatory reactions. It is a complex disease that presents with a range of symptoms, with pain and infertility being the most common. Along with severe dysmenorrhea, cyclic and acyclic lower abdominal pain, cyclic dysuria and dyschezia, dyspareunia, and infertility, there are also nonspecific complaints that can cause confusion and make endometriosis the chameleon among gynecological diseases. These symptoms include unspecific intestinal complaints, cyclic diarrhea, but also constipation, nausea, vomiting, and stomach complaints. It appears that in addition to general bowel symptoms, there are also specific symptoms related to endometriosis such as cyclic bloating of the abdomen, known as endo belly. During the second half of the menstrual cycle leading up to menstruation, the abdomen becomes increasingly bloated causing discomfort and pain due to elevated sensitivity of the intestinal wall. Patients with endometriosis exhibit a reduced stretch pain threshold of the intestinal wall. Here, we review the endo belly, for the first time, pathophysiology and the influence of other diseases (such as irritable bowel syndrome—IBS), microbiome, hormonal levels, inflammation, and diet on the presentation of this condition. |
format | Online Article Text |
id | pubmed-10671958 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-106719582023-11-19 Endo Belly: What Is It and Why Does It Happen?—A Narrative Review Velho, Renata Voltolini Werner, Franziska Mechsner, Sylvia J Clin Med Review Endometriosis is a chronic inflammatory disease where endometrial-like lesions settle outside the uterus, resulting in extensive inflammatory reactions. It is a complex disease that presents with a range of symptoms, with pain and infertility being the most common. Along with severe dysmenorrhea, cyclic and acyclic lower abdominal pain, cyclic dysuria and dyschezia, dyspareunia, and infertility, there are also nonspecific complaints that can cause confusion and make endometriosis the chameleon among gynecological diseases. These symptoms include unspecific intestinal complaints, cyclic diarrhea, but also constipation, nausea, vomiting, and stomach complaints. It appears that in addition to general bowel symptoms, there are also specific symptoms related to endometriosis such as cyclic bloating of the abdomen, known as endo belly. During the second half of the menstrual cycle leading up to menstruation, the abdomen becomes increasingly bloated causing discomfort and pain due to elevated sensitivity of the intestinal wall. Patients with endometriosis exhibit a reduced stretch pain threshold of the intestinal wall. Here, we review the endo belly, for the first time, pathophysiology and the influence of other diseases (such as irritable bowel syndrome—IBS), microbiome, hormonal levels, inflammation, and diet on the presentation of this condition. MDPI 2023-11-19 /pmc/articles/PMC10671958/ /pubmed/38002788 http://dx.doi.org/10.3390/jcm12227176 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Velho, Renata Voltolini Werner, Franziska Mechsner, Sylvia Endo Belly: What Is It and Why Does It Happen?—A Narrative Review |
title | Endo Belly: What Is It and Why Does It Happen?—A Narrative Review |
title_full | Endo Belly: What Is It and Why Does It Happen?—A Narrative Review |
title_fullStr | Endo Belly: What Is It and Why Does It Happen?—A Narrative Review |
title_full_unstemmed | Endo Belly: What Is It and Why Does It Happen?—A Narrative Review |
title_short | Endo Belly: What Is It and Why Does It Happen?—A Narrative Review |
title_sort | endo belly: what is it and why does it happen?—a narrative review |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10671958/ https://www.ncbi.nlm.nih.gov/pubmed/38002788 http://dx.doi.org/10.3390/jcm12227176 |
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