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Virtual Insights into Natural Compounds as Potential 5α-Reductase Type II Inhibitors: A Structure-Based Screening and Molecular Dynamics Simulation Study
Androgenic alopecia (AGA) is a dermatological disease with psychosocial consequences for those who experience hair loss. AGA is linked to an increase in androgen levels caused by an excess of dihydrotestosterone in blood capillaries produced from testosterone by 5α-reductase type II (5αR2), which is...
Autores principales: | Shaikh, Sibhghatulla, Ali, Shahid, Lim, Jeong Ho, Ahmad, Khurshid, Han, Ki Soo, Lee, Eun Ju, Choi, Inho |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10671996/ https://www.ncbi.nlm.nih.gov/pubmed/38004292 http://dx.doi.org/10.3390/life13112152 |
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