Cargando…

Exome Sequencing Reveals Novel Germline Variants in Breast Cancer Patients in the Southernmost Region of Thailand

Germline carriers of pathogenic variants in cancer susceptibility genes are at an increased risk of breast cancer (BC). We characterized germline variants in a cohort of 151 patients diagnosed with epithelial BC in the southernmost region of Thailand, where the predominant ethnicity differs from tha...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sukpan, Panupong, Sangkhathat, Surasak, Sriplung, Hutcha, Laochareonsuk, Wison, Choochuen, Pongsakorn, Auseng, Nasuha, Khoonjan, Weerawan, Salaeh, Rusta, Thangnaphadol, Kornchanok, Wanawanakorn, Kasemsun, Kanokwiroon, Kanyanatt
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10672121/ https://www.ncbi.nlm.nih.gov/pubmed/38003901 http://dx.doi.org/10.3390/jpm13111587

Ejemplares similares

Prevalence of Pathogenic Germline Mutations in 13 Hereditary Cancer-Related Genes in Breast Cancer Patients in Narathiwat Province, Thailand
por: Sukpan, Panupong, et al.
Publicado: (2023)

Juvenile Hyaline Fibromatosis: Report of a Case with a Novel ANTXR2 Gene Mutation
por: Choochuen, Pongsakorn, et al.
Publicado: (2022)

Stuttering priapism in a pediatric patient with pheochromocytoma-induced thrombocytosis
por: Boonchai, Sarayuth, et al.
Publicado: (2022)

A novel pathogenesis concept of biliary atresia approached by combined molecular strategies
por: Laochareonsuk, Wison, et al.
Publicado: (2022)

Population-based prevalence study of common congenital malformations of the alimentary tract and abdominal wall in Thailand: a study using data from the National Health Security Office
por: Sirichamratsakul, Kulpreeya, et al.
Publicado: (2023)

Impact of EFEMP1 on the survival outcome of biliary atresia in Thai infants
por: Laochareonsuk, Wison, et al.
Publicado: (2022)

Enrichment of T-cell proliferation and memory gene signatures of CD79A/CD40 costimulatory domain potentiates CD19CAR-T cell functions
por: Ung, Socheatraksmey, et al.
Publicado: (2022)

Genomics-Driven Precision Medicine in Pediatric Solid Tumors
por: Suthapot, Praewa, et al.
Publicado: (2023)

Response of cardiac endothelial nitric oxide synthase to plasma viscosity modulation in acute isovolemic hemodilution
por: Kanokwiroon, Kanyanatt, et al.
Publicado: (2014)

Interruptin C, a Radioprotective Agent, Derived from Cyclosorus terminans Protect Normal Breast MCF-10A and Human Keratinocyte HaCaT Cells against Radiation-Induced Damage
por: Chumsuwan, Nipha, et al.
Publicado: (2022)

Integrated bioinformatic analysis of potential biomarkers of poor prognosis in triple-negative breast cancer
por: Bissanum, Rassanee, et al.
Publicado: (2022)

Immunohistochemistry-based molecular subtyping of triple-negative breast cancer and its prognostic significance
por: Leeha, Marisa, et al.
Publicado: (2023)

A rapid rise in hormone receptor-positive and HER2-positive breast cancer subtypes in Southern Thai women: A population-based study in Songkhla
por: Chuaychai, Aungkana, et al.
Publicado: (2022)

The dose dependent in vitro responses of MCF-7 and MDA-MB-231 cell lines to extracts of Vatica diospyroides symington type SS fruit include effects on mode of cell death
por: Srisawat, Theera, et al.
Publicado: (2015)

Anticancer Potential of Fruit Extracts from Vatica diospyroides Symington Type SS and Their Effect on Program Cell Death of Cervical Cancer Cell Lines
por: Chothiphirat, Atchara, et al.
Publicado: (2019)

Molecular Classification Models for Triple Negative Breast Cancer Subtype Using Machine Learning
por: Bissanum, Rassanee, et al.
Publicado: (2021)

Anticancer mechanism of 7-α-hydroxyfrullanolide on microtubules and computational prediction of its target binding in triple-negative breast cancer cells
por: Chimplee, Siriphorn, et al.
Publicado: (2022)

The First Report of Multicentric Carpotarsal Osteolysis Syndrome Caused by MAFB Mutation in Asian
por: Choochuen, Pongsakorn, et al.
Publicado: (2018)

Transcriptomic Analysis of Subtype-Specific Tyrosine Kinases as Triple Negative Breast Cancer Biomarkers
por: Limsakul, Praopim, et al.
Publicado: (2023)

Southernmost Carriers of HTLV‐I/II in the World
por: Cartier, Luis, et al.
Publicado: (1993)

Nubian Levallois technology associated with southernmost Neanderthals
por: Blinkhorn, James, et al.
Publicado: (2021)

Extracts from Vatica diospyroides Type SS Fruit Show Low Dose Activity against MDA-MB-468 Breast Cancer Cell-Line via Apoptotic Action
por: Srisawat, Theera, et al.
Publicado: (2014)

Anticancer Effects and Molecular Action of 7-α-Hydroxyfrullanolide in G2/M-Phase Arrest and Apoptosis in Triple Negative Breast Cancer Cells
por: Chimplee, Siriphorn, et al.
Publicado: (2022)

The Anticancer Effects of FDI-6, a FOXM1 Inhibitor, on Triple Negative Breast Cancer
por: Ulhaka, Karan, et al.
Publicado: (2021)

Survival rates in the world's southernmost forest bird community
por: Sandvig, Erik M., et al.
Publicado: (2023)

CPIRD: A successful Thai programme to produce clinically competent medical graduates
por: Yi, Yanhua, et al.
Publicado: (2015)

Maternal Age-Specific Rates for Trisomy 21 and Common Autosomal Trisomies in Fetuses from a Single Diagnostic Center in Thailand
por: Jaruthamsophon, Kanoot, et al.
Publicado: (2016)

Trends in incidence of uterine cancer in Songkhla, Southern Thailand
por: Saeaib, Nungrutai, et al.
Publicado: (2018)

The effect of Pap smear screening on cervical cancer stage among southern Thai women
por: Niu, Li, et al.
Publicado: (2019)

Geographical inequality in service utilization for primary aldosteronism screening: spatial epidemiological study in Southern Thailand
por: Suntornlohanakul, Onnicha, et al.
Publicado: (2022)

The Spatial Epidemiology of Patients Who Were Screened for and Diagnosed With Primary Aldosteronism in Southern Thailand
por: Suntornlohanakul, Onnicha, et al.
Publicado: (2021)

Role of innate lymphoid cells in obesity and metabolic disease
por: Saetang, Jirakrit, et al.
Publicado: (2018)

The use of a multiple imputation method to investigate the trends in Histologic types of lung cancer in Songkhla province, Thailand, 1989–2013
por: Sriplung, Hutcha, et al.
Publicado: (2016)

Reconsideration of the nomadic condition of the southernmost Guachichiles based on the relationship with their environment
por: Mellink, Eric, et al.
Publicado: (2018)

The 1918 influenza pandemic in Montevideo: The southernmost capital city in the Americas
por: Cristina, Juan, et al.
Publicado: (2019)

Assessment of Culex pipiens bioforms in the world’s southernmost distribution limit
por: Cardo, María Victoria, et al.
Publicado: (2020)

Impact of mid Eocene greenhouse warming on America’s southernmost floras
por: Fernández, Damián A., et al.
Publicado: (2021)

Active construction of southernmost Tibet revealed by deep seismic imaging
por: Lu, Zhanwu, et al.
Publicado: (2022)

No Prognostic Impact of p53 and P-Glycoprotein Expression in Patients with Diffuse Large B-Cell Lymphoma
por: Rujirojindakul, Pairaya, et al.
Publicado: (2011)

Comparison of Cholangiocarcinoma and Hepatocellular Carcinoma Incidence Trends from 1993 to 2012 in Lampang, Thailand
por: Cao, Pianpian, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_24ec5tqrdu93qfd2kpb6q9cn60