Intestinal Paneth cell differentiation relies on asymmetric regulation of Wnt signaling by Daam1/2

The mammalian intestine is one of the most rapidly self-renewing tissues, driven by stem cells residing at the crypt bottom. Paneth cells form a major element of the niche microenvironment providing various growth factors to orchestrate intestinal stem cell homeostasis, such as Wnt3. Different Wnt l...

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Detalles Bibliográficos
Autores principales: Colozza, Gabriele, Lee, Heetak, Merenda, Alessandra, Wu, Szu-Hsien Sam, Català-Bordes, Andrea, Radaszkiewicz, Tomasz W., Jordens, Ingrid, Lee, Ji-Hyun, Bamford, Aileen-Diane, Farnhammer, Fiona, Low, Teck Yew, Maurice, Madelon M., Bryja, Vítězslav, Kim, Jihoon, Koo, Bon-Kyoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10672176/
https://www.ncbi.nlm.nih.gov/pubmed/38000028
http://dx.doi.org/10.1126/sciadv.adh9673

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