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Pharmacological Modulation of β-Catenin Preserves Endothelial Barrier Integrity and Mitigates Retinal Vascular Permeability and Inflammation

Compromised blood-retinal barrier (BRB) integrity is a significant factor in ocular diseases like uveitis and retinopathies, leading to pathological vascular permeability and retinal edema. Adherens and tight junction (AJ and TJ) dysregulation due to retinal inflammation plays a pivotal role in BRB...

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Detalles Bibliográficos
Autores principales: Rudraraju, Madhuri, Shan, Shengshuai, Liu, Fang, Tyler, Jennifer, Caldwell, Ruth B., Somanath, Payaningal R., Narayanan, S. Priya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10672253/
https://www.ncbi.nlm.nih.gov/pubmed/38002758
http://dx.doi.org/10.3390/jcm12227145