Cargando…

Perioperative Right Ventricular Dysfunction and Abnormalities of the Tricuspid Valve Apparatus in Patients Undergoing Cardiac Surgery

Right ventricular (RV) dysfunction frequently occurs after cardiac surgery and is linked to adverse postoperative outcomes, including mortality, reintubation, stroke, and prolonged ICU stays. While various criteria using echocardiography and hemodynamic parameters have been proposed, a consensus rem...

Descripción completa

Detalles Bibliográficos
Autores principales: Mattei, Alessia, Strumia, Alessandro, Benedetto, Maria, Nenna, Antonio, Schiavoni, Lorenzo, Barbato, Raffaele, Mastroianni, Ciro, Giacinto, Omar, Lusini, Mario, Chello, Massimo, Carassiti, Massimiliano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10672350/
https://www.ncbi.nlm.nih.gov/pubmed/38002763
http://dx.doi.org/10.3390/jcm12227152
_version_ 1785149514467770368
author Mattei, Alessia
Strumia, Alessandro
Benedetto, Maria
Nenna, Antonio
Schiavoni, Lorenzo
Barbato, Raffaele
Mastroianni, Ciro
Giacinto, Omar
Lusini, Mario
Chello, Massimo
Carassiti, Massimiliano
author_facet Mattei, Alessia
Strumia, Alessandro
Benedetto, Maria
Nenna, Antonio
Schiavoni, Lorenzo
Barbato, Raffaele
Mastroianni, Ciro
Giacinto, Omar
Lusini, Mario
Chello, Massimo
Carassiti, Massimiliano
author_sort Mattei, Alessia
collection PubMed
description Right ventricular (RV) dysfunction frequently occurs after cardiac surgery and is linked to adverse postoperative outcomes, including mortality, reintubation, stroke, and prolonged ICU stays. While various criteria using echocardiography and hemodynamic parameters have been proposed, a consensus remains elusive. Distinctive RV anatomical features include its thin wall, which presents a triangular shape in a lateral view and a crescent shape in a cross-sectional view. Principal causes of RV dysfunction after cardiac surgery encompass ischemic reperfusion injury, prolonged ischemic time, choice of cardioplegia and its administration, cardiopulmonary bypass weaning characteristics, and preoperative risk factors. Post-left ventricular assist device (LVAD) implantation RV dysfunction is common but often transient, with a favorable prognosis upon resolution. There is an ongoing debate regarding the benefits of concomitant surgical repair of the RV in the presence of regurgitation. According to the literature, the gold standard techniques for assessing RV function are cardiac magnetic resonance imaging and hemodynamic assessment using thermodilution. Echocardiography is widely favored for perioperative RV function evaluation due to its accessibility, reproducibility, non-invasiveness, and cost-effectiveness. Although other techniques exist for RV function assessment, they are less common in clinical practice. Clinical management strategies focus on early detection and include intravenous drugs (inotropes and vasodilators), inhalation drugs (pulmonary vasodilators), ventilator strategies, volume management, and mechanical support. Bridging research gaps in this field is crucial to improving clinical outcomes associated with RV dysfunction in the near future.
format Online
Article
Text
id pubmed-10672350
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-106723502023-11-17 Perioperative Right Ventricular Dysfunction and Abnormalities of the Tricuspid Valve Apparatus in Patients Undergoing Cardiac Surgery Mattei, Alessia Strumia, Alessandro Benedetto, Maria Nenna, Antonio Schiavoni, Lorenzo Barbato, Raffaele Mastroianni, Ciro Giacinto, Omar Lusini, Mario Chello, Massimo Carassiti, Massimiliano J Clin Med Review Right ventricular (RV) dysfunction frequently occurs after cardiac surgery and is linked to adverse postoperative outcomes, including mortality, reintubation, stroke, and prolonged ICU stays. While various criteria using echocardiography and hemodynamic parameters have been proposed, a consensus remains elusive. Distinctive RV anatomical features include its thin wall, which presents a triangular shape in a lateral view and a crescent shape in a cross-sectional view. Principal causes of RV dysfunction after cardiac surgery encompass ischemic reperfusion injury, prolonged ischemic time, choice of cardioplegia and its administration, cardiopulmonary bypass weaning characteristics, and preoperative risk factors. Post-left ventricular assist device (LVAD) implantation RV dysfunction is common but often transient, with a favorable prognosis upon resolution. There is an ongoing debate regarding the benefits of concomitant surgical repair of the RV in the presence of regurgitation. According to the literature, the gold standard techniques for assessing RV function are cardiac magnetic resonance imaging and hemodynamic assessment using thermodilution. Echocardiography is widely favored for perioperative RV function evaluation due to its accessibility, reproducibility, non-invasiveness, and cost-effectiveness. Although other techniques exist for RV function assessment, they are less common in clinical practice. Clinical management strategies focus on early detection and include intravenous drugs (inotropes and vasodilators), inhalation drugs (pulmonary vasodilators), ventilator strategies, volume management, and mechanical support. Bridging research gaps in this field is crucial to improving clinical outcomes associated with RV dysfunction in the near future. MDPI 2023-11-17 /pmc/articles/PMC10672350/ /pubmed/38002763 http://dx.doi.org/10.3390/jcm12227152 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Mattei, Alessia
Strumia, Alessandro
Benedetto, Maria
Nenna, Antonio
Schiavoni, Lorenzo
Barbato, Raffaele
Mastroianni, Ciro
Giacinto, Omar
Lusini, Mario
Chello, Massimo
Carassiti, Massimiliano
Perioperative Right Ventricular Dysfunction and Abnormalities of the Tricuspid Valve Apparatus in Patients Undergoing Cardiac Surgery
title Perioperative Right Ventricular Dysfunction and Abnormalities of the Tricuspid Valve Apparatus in Patients Undergoing Cardiac Surgery
title_full Perioperative Right Ventricular Dysfunction and Abnormalities of the Tricuspid Valve Apparatus in Patients Undergoing Cardiac Surgery
title_fullStr Perioperative Right Ventricular Dysfunction and Abnormalities of the Tricuspid Valve Apparatus in Patients Undergoing Cardiac Surgery
title_full_unstemmed Perioperative Right Ventricular Dysfunction and Abnormalities of the Tricuspid Valve Apparatus in Patients Undergoing Cardiac Surgery
title_short Perioperative Right Ventricular Dysfunction and Abnormalities of the Tricuspid Valve Apparatus in Patients Undergoing Cardiac Surgery
title_sort perioperative right ventricular dysfunction and abnormalities of the tricuspid valve apparatus in patients undergoing cardiac surgery
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10672350/
https://www.ncbi.nlm.nih.gov/pubmed/38002763
http://dx.doi.org/10.3390/jcm12227152
work_keys_str_mv AT matteialessia perioperativerightventriculardysfunctionandabnormalitiesofthetricuspidvalveapparatusinpatientsundergoingcardiacsurgery
AT strumiaalessandro perioperativerightventriculardysfunctionandabnormalitiesofthetricuspidvalveapparatusinpatientsundergoingcardiacsurgery
AT benedettomaria perioperativerightventriculardysfunctionandabnormalitiesofthetricuspidvalveapparatusinpatientsundergoingcardiacsurgery
AT nennaantonio perioperativerightventriculardysfunctionandabnormalitiesofthetricuspidvalveapparatusinpatientsundergoingcardiacsurgery
AT schiavonilorenzo perioperativerightventriculardysfunctionandabnormalitiesofthetricuspidvalveapparatusinpatientsundergoingcardiacsurgery
AT barbatoraffaele perioperativerightventriculardysfunctionandabnormalitiesofthetricuspidvalveapparatusinpatientsundergoingcardiacsurgery
AT mastroianniciro perioperativerightventriculardysfunctionandabnormalitiesofthetricuspidvalveapparatusinpatientsundergoingcardiacsurgery
AT giacintoomar perioperativerightventriculardysfunctionandabnormalitiesofthetricuspidvalveapparatusinpatientsundergoingcardiacsurgery
AT lusinimario perioperativerightventriculardysfunctionandabnormalitiesofthetricuspidvalveapparatusinpatientsundergoingcardiacsurgery
AT chellomassimo perioperativerightventriculardysfunctionandabnormalitiesofthetricuspidvalveapparatusinpatientsundergoingcardiacsurgery
AT carassitimassimiliano perioperativerightventriculardysfunctionandabnormalitiesofthetricuspidvalveapparatusinpatientsundergoingcardiacsurgery