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Further Association of Germline CHEK2 Loss-of-Function Variants with Testicular Germ Cell Tumors

Testicular germ cell tumors (TGCTs) represent the most frequent malignancy in young adult men and have one the highest heritability rates among all cancers. A recent multicenter case–control study identified CHEK2 as the first moderate-penetrance TGCT predisposition gene. Here, we analyzed CHEK2 in...

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Detalles Bibliográficos
Autores principales: Kirchner, Kira, Seidel, Christoph, Paulsen, Finn-Ole, Sievers, Bianca, Bokemeyer, Carsten, Lessel, Davor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10672725/
https://www.ncbi.nlm.nih.gov/pubmed/38002677
http://dx.doi.org/10.3390/jcm12227065

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