Anti-Trypanosoma cruzi Activity, Mutagenicity, Hepatocytotoxicity and Nitroreductase Enzyme Evaluation of 3-Nitrotriazole, 2-Nitroimidazole and Triazole Derivatives

Chagas disease (CD), which is caused by Trypanosoma cruzi and was discovered more than 100 years ago, remains the leading cause of death from parasitic diseases in the Americas. As a curative treatment is only available for the acute phase of CD, the search for new therapeutic options is urgent. In...

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Detalles Bibliográficos
Autores principales: Menozzi, Cheyene Almeida Celestino, França, Rodolfo Rodrigo Florido, Luccas, Pedro Henrique, Baptista, Mayara dos Santos, Fernandes, Tácio Vinício Amorim, Hoelz, Lucas Villas Bôas, Sales Junior, Policarpo Ademar, Murta, Silvane Maria Fonseca, Romanha, Alvaro, Galvão, Bárbara Verena Dias, Macedo, Marcela de Oliveira, Goldstein, Alana da Cunha, Araujo-Lima, Carlos Fernando, Felzenszwalb, Israel, Nonato, Maria Cristina, Castelo-Branco, Frederico Silva, Boechat, Nubia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10672842/
https://www.ncbi.nlm.nih.gov/pubmed/38005183
http://dx.doi.org/10.3390/molecules28227461

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