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AlphaFold Blindness to Topological Barriers Affects Its Ability to Correctly Predict Proteins’ Topology

AlphaFold is a groundbreaking deep learning tool for protein structure prediction. It achieved remarkable accuracy in modeling many 3D structures while taking as the user input only the known amino acid sequence of proteins in question. Intriguingly though, in the early steps of each individual stru...

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Detalles Bibliográficos
Autores principales: Dabrowski-Tumanski, Pawel, Stasiak, Andrzej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10672856/
https://www.ncbi.nlm.nih.gov/pubmed/38005184
http://dx.doi.org/10.3390/molecules28227462

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