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In Vitro and In Vivo Crosstalk between Type I IFN and IL-8 Responses in SARS-CoV-2 Infection

COVID-19 patients show characteristic over-expression of different cytokines that may interfere with the interferon (IFN) response, delaying its production. Within the overexpressed cytokines, IL-8 plays a key role, and it may impede IFN-I activation. PBMC from eight healthy donors were exposed to 2...

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Detalles Bibliográficos
Autores principales: Biava, Mirella, Notari, Stefania, Grassi, Germana, Bordi, Licia, Tartaglia, Eleonora, Agrati, Chiara, Cimini, Eleonora, Sberna, Giuseppe, Nicastri, Emanuele, Antinori, Andrea, Girardi, Enrico, Vaia, Francesco, Maggi, Fabrizio, Lalle, Eleonora
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10672883/
https://www.ncbi.nlm.nih.gov/pubmed/38004798
http://dx.doi.org/10.3390/microorganisms11112787