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Metabolome and Transcriptome Combinatory Profiling Reveals Fluconazole Resistance Mechanisms of Trichosporon asahii and the Role of Farnesol in Fluconazole Tolerance

Trichosporon asahii is a basidiomycete yeast that is pathogenic to humans and animals, and fluconazole-resistant strains have recently increased. Farnesol secreted by fungi is a factor that causes variations in fluconazole resistance; however, few studies have explored the underlying mechanisms. The...

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Detalles Bibliográficos
Autores principales: Ma, Xiaoping, Yang, Wanling, Yang, Aining, Chen, Dong, Wang, Chengdong, Ling, Shanshan, Cao, Sanjie, Zuo, Zhicai, Wang, Ya, Zhong, Zhijun, Peng, Guangneng, He, Ming, Gu, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10672884/
https://www.ncbi.nlm.nih.gov/pubmed/38004810
http://dx.doi.org/10.3390/microorganisms11112798