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Microcatheter-Directed Thrombolysis Using Recombinant Tissue Plasminogen Activator for the Treatment of Acute Superior Mesenteric Artery Embolism: A Case Report
Background: Acute mesenteric ischemia (AMI) is a life-threatening condition, and in 50% of patients, AMI is caused by acute superior mesenteric artery (SMA) embolism. Endovascular treatment is increasingly being considered the primary modality in selected cases. Many studies have reported that percu...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10672895/ https://www.ncbi.nlm.nih.gov/pubmed/38003939 http://dx.doi.org/10.3390/medicina59111889 |
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author | Kim, Yang-Won Choi, Ho-Cheol Yang, Won-Jeong Koo, Byeong-Ju Ahn, Jae-Kyeong Lee, Jeong-Pyo Na, Jae-Bum Jo, Sa-Hong Park, Sung-Eun Won, Jung-Ho |
author_facet | Kim, Yang-Won Choi, Ho-Cheol Yang, Won-Jeong Koo, Byeong-Ju Ahn, Jae-Kyeong Lee, Jeong-Pyo Na, Jae-Bum Jo, Sa-Hong Park, Sung-Eun Won, Jung-Ho |
author_sort | Kim, Yang-Won |
collection | PubMed |
description | Background: Acute mesenteric ischemia (AMI) is a life-threatening condition, and in 50% of patients, AMI is caused by acute superior mesenteric artery (SMA) embolism. Endovascular treatment is increasingly being considered the primary modality in selected cases. Many studies have reported that percutaneous aspiration embolectomy using a guiding catheter and thrombolysis with recombinant tissue plasminogen activator (rtPA) are effective in treating SMA embolism. However, no reports on treating SMA embolism using rtPA administered via a microcatheter exist. Case presentation: A 64-year-old man with underlying atrial fibrillation presented with acute SMA embolism revealed using computed tomography (CT). rtPA (total 3 mg) was carefully administered into the occluded SMA through a microcatheter. No complications occurred, and complete revascularization of the SMA was revealed on follow-up CT. Conclusions: Compared with previous reports, this case report reveals that successful revascularization can be achieved using rtPA administered via a microcatheter, with a low dose of rtPA and a short duration of thrombolysis. |
format | Online Article Text |
id | pubmed-10672895 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-106728952023-10-24 Microcatheter-Directed Thrombolysis Using Recombinant Tissue Plasminogen Activator for the Treatment of Acute Superior Mesenteric Artery Embolism: A Case Report Kim, Yang-Won Choi, Ho-Cheol Yang, Won-Jeong Koo, Byeong-Ju Ahn, Jae-Kyeong Lee, Jeong-Pyo Na, Jae-Bum Jo, Sa-Hong Park, Sung-Eun Won, Jung-Ho Medicina (Kaunas) Case Report Background: Acute mesenteric ischemia (AMI) is a life-threatening condition, and in 50% of patients, AMI is caused by acute superior mesenteric artery (SMA) embolism. Endovascular treatment is increasingly being considered the primary modality in selected cases. Many studies have reported that percutaneous aspiration embolectomy using a guiding catheter and thrombolysis with recombinant tissue plasminogen activator (rtPA) are effective in treating SMA embolism. However, no reports on treating SMA embolism using rtPA administered via a microcatheter exist. Case presentation: A 64-year-old man with underlying atrial fibrillation presented with acute SMA embolism revealed using computed tomography (CT). rtPA (total 3 mg) was carefully administered into the occluded SMA through a microcatheter. No complications occurred, and complete revascularization of the SMA was revealed on follow-up CT. Conclusions: Compared with previous reports, this case report reveals that successful revascularization can be achieved using rtPA administered via a microcatheter, with a low dose of rtPA and a short duration of thrombolysis. MDPI 2023-10-24 /pmc/articles/PMC10672895/ /pubmed/38003939 http://dx.doi.org/10.3390/medicina59111889 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Case Report Kim, Yang-Won Choi, Ho-Cheol Yang, Won-Jeong Koo, Byeong-Ju Ahn, Jae-Kyeong Lee, Jeong-Pyo Na, Jae-Bum Jo, Sa-Hong Park, Sung-Eun Won, Jung-Ho Microcatheter-Directed Thrombolysis Using Recombinant Tissue Plasminogen Activator for the Treatment of Acute Superior Mesenteric Artery Embolism: A Case Report |
title | Microcatheter-Directed Thrombolysis Using Recombinant Tissue Plasminogen Activator for the Treatment of Acute Superior Mesenteric Artery Embolism: A Case Report |
title_full | Microcatheter-Directed Thrombolysis Using Recombinant Tissue Plasminogen Activator for the Treatment of Acute Superior Mesenteric Artery Embolism: A Case Report |
title_fullStr | Microcatheter-Directed Thrombolysis Using Recombinant Tissue Plasminogen Activator for the Treatment of Acute Superior Mesenteric Artery Embolism: A Case Report |
title_full_unstemmed | Microcatheter-Directed Thrombolysis Using Recombinant Tissue Plasminogen Activator for the Treatment of Acute Superior Mesenteric Artery Embolism: A Case Report |
title_short | Microcatheter-Directed Thrombolysis Using Recombinant Tissue Plasminogen Activator for the Treatment of Acute Superior Mesenteric Artery Embolism: A Case Report |
title_sort | microcatheter-directed thrombolysis using recombinant tissue plasminogen activator for the treatment of acute superior mesenteric artery embolism: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10672895/ https://www.ncbi.nlm.nih.gov/pubmed/38003939 http://dx.doi.org/10.3390/medicina59111889 |
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