Attenuated Replication-Competent Herpes Simplex Virus Expressing an ECM-Modifying Transgene Hyaluronan Synthase 2 of Naked Mole Rat in Oncolytic Gene Therapy

Herpes simplex virus (HSV) has proven successful in treating human cancer. Since the approval of talimogene laherparepvec (T-VEC) in 2015, HSV has been thoroughly researched to discover novel mechanisms to combat cancer and treat other diseases. Another HSV-based drug, beremagene geperpavec (B-VEC),...

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Detalles Bibliográficos
Autores principales: Palomäki, Jussi, Kalke, Kiira, Orpana, Julius, Lund, Liisa, Frejborg, Fanny, Paavilainen, Henrik, Järveläinen, Hannu, Hukkanen, Veijo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10673056/
https://www.ncbi.nlm.nih.gov/pubmed/38004669
http://dx.doi.org/10.3390/microorganisms11112657

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10673056/
https://www.ncbi.nlm.nih.gov/pubmed/38004669
http://dx.doi.org/10.3390/microorganisms11112657

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