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Design, Simulation and Multi-Objective Optimization of a Micro-Scale Gearbox for a Novel Rotary Peristaltic Pump
Peristaltic pumps are widely used in biomedical applications to ensure the safe flow of sterile or medical fluids. They are commonly employed for drug injections, IV fluids, and blood separation (apheresis). These pumps operate through a progressive contraction or expansion along a flexible tube, en...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10673108/ https://www.ncbi.nlm.nih.gov/pubmed/38004956 http://dx.doi.org/10.3390/mi14112099 |
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author | Rogkas, Nikolaos Pelekis, Matthaios Manios, Alexandros Anastasiadis, Alexandros Vasileiou, Georgios Tsoukalis, Achilleas Manopoulos, Christos Spitas, Vasilios |
author_facet | Rogkas, Nikolaos Pelekis, Matthaios Manios, Alexandros Anastasiadis, Alexandros Vasileiou, Georgios Tsoukalis, Achilleas Manopoulos, Christos Spitas, Vasilios |
author_sort | Rogkas, Nikolaos |
collection | PubMed |
description | Peristaltic pumps are widely used in biomedical applications to ensure the safe flow of sterile or medical fluids. They are commonly employed for drug injections, IV fluids, and blood separation (apheresis). These pumps operate through a progressive contraction or expansion along a flexible tube, enabling fluid flow. They are also utilized in industrial applications for sanitary fluid transport, corrosive fluid handling, and novel pharmacological delivery systems. This research provides valuable insights into the selection and optimal design of the powertrain stages for peristaltic pumps implemented in drug delivery systems. The focus of this paper lies in the simulation and optimization of the performance of a power transmission gearbox by examining the energy consumption, sound levels, reliability, and volume as output metrics. The components of the powertrain consist of a helical gear pair for the first stage, a bevel gear pair for the second one, and finally a planetary transmission. Through extensive simulations, the model exhibits promising results, achieving an efficiency of up to 90%. Furthermore, alternative configurations were investigated to optimize the overall performance of the powertrain. This process has been simulated by employing the KISSsoft/KISSsys software package. The findings of this investigation contribute to advancements in the field of biomedical engineering and hold significant potential for improving the efficiency, reliability, and performance of drug delivery mechanisms. |
format | Online Article Text |
id | pubmed-10673108 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-106731082023-11-14 Design, Simulation and Multi-Objective Optimization of a Micro-Scale Gearbox for a Novel Rotary Peristaltic Pump Rogkas, Nikolaos Pelekis, Matthaios Manios, Alexandros Anastasiadis, Alexandros Vasileiou, Georgios Tsoukalis, Achilleas Manopoulos, Christos Spitas, Vasilios Micromachines (Basel) Article Peristaltic pumps are widely used in biomedical applications to ensure the safe flow of sterile or medical fluids. They are commonly employed for drug injections, IV fluids, and blood separation (apheresis). These pumps operate through a progressive contraction or expansion along a flexible tube, enabling fluid flow. They are also utilized in industrial applications for sanitary fluid transport, corrosive fluid handling, and novel pharmacological delivery systems. This research provides valuable insights into the selection and optimal design of the powertrain stages for peristaltic pumps implemented in drug delivery systems. The focus of this paper lies in the simulation and optimization of the performance of a power transmission gearbox by examining the energy consumption, sound levels, reliability, and volume as output metrics. The components of the powertrain consist of a helical gear pair for the first stage, a bevel gear pair for the second one, and finally a planetary transmission. Through extensive simulations, the model exhibits promising results, achieving an efficiency of up to 90%. Furthermore, alternative configurations were investigated to optimize the overall performance of the powertrain. This process has been simulated by employing the KISSsoft/KISSsys software package. The findings of this investigation contribute to advancements in the field of biomedical engineering and hold significant potential for improving the efficiency, reliability, and performance of drug delivery mechanisms. MDPI 2023-11-14 /pmc/articles/PMC10673108/ /pubmed/38004956 http://dx.doi.org/10.3390/mi14112099 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Rogkas, Nikolaos Pelekis, Matthaios Manios, Alexandros Anastasiadis, Alexandros Vasileiou, Georgios Tsoukalis, Achilleas Manopoulos, Christos Spitas, Vasilios Design, Simulation and Multi-Objective Optimization of a Micro-Scale Gearbox for a Novel Rotary Peristaltic Pump |
title | Design, Simulation and Multi-Objective Optimization of a Micro-Scale Gearbox for a Novel Rotary Peristaltic Pump |
title_full | Design, Simulation and Multi-Objective Optimization of a Micro-Scale Gearbox for a Novel Rotary Peristaltic Pump |
title_fullStr | Design, Simulation and Multi-Objective Optimization of a Micro-Scale Gearbox for a Novel Rotary Peristaltic Pump |
title_full_unstemmed | Design, Simulation and Multi-Objective Optimization of a Micro-Scale Gearbox for a Novel Rotary Peristaltic Pump |
title_short | Design, Simulation and Multi-Objective Optimization of a Micro-Scale Gearbox for a Novel Rotary Peristaltic Pump |
title_sort | design, simulation and multi-objective optimization of a micro-scale gearbox for a novel rotary peristaltic pump |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10673108/ https://www.ncbi.nlm.nih.gov/pubmed/38004956 http://dx.doi.org/10.3390/mi14112099 |
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