Cargando…

Design, Simulation and Multi-Objective Optimization of a Micro-Scale Gearbox for a Novel Rotary Peristaltic Pump

Peristaltic pumps are widely used in biomedical applications to ensure the safe flow of sterile or medical fluids. They are commonly employed for drug injections, IV fluids, and blood separation (apheresis). These pumps operate through a progressive contraction or expansion along a flexible tube, en...

Descripción completa

Detalles Bibliográficos
Autores principales: Rogkas, Nikolaos, Pelekis, Matthaios, Manios, Alexandros, Anastasiadis, Alexandros, Vasileiou, Georgios, Tsoukalis, Achilleas, Manopoulos, Christos, Spitas, Vasilios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10673108/
https://www.ncbi.nlm.nih.gov/pubmed/38004956
http://dx.doi.org/10.3390/mi14112099
_version_ 1785149579705974784
author Rogkas, Nikolaos
Pelekis, Matthaios
Manios, Alexandros
Anastasiadis, Alexandros
Vasileiou, Georgios
Tsoukalis, Achilleas
Manopoulos, Christos
Spitas, Vasilios
author_facet Rogkas, Nikolaos
Pelekis, Matthaios
Manios, Alexandros
Anastasiadis, Alexandros
Vasileiou, Georgios
Tsoukalis, Achilleas
Manopoulos, Christos
Spitas, Vasilios
author_sort Rogkas, Nikolaos
collection PubMed
description Peristaltic pumps are widely used in biomedical applications to ensure the safe flow of sterile or medical fluids. They are commonly employed for drug injections, IV fluids, and blood separation (apheresis). These pumps operate through a progressive contraction or expansion along a flexible tube, enabling fluid flow. They are also utilized in industrial applications for sanitary fluid transport, corrosive fluid handling, and novel pharmacological delivery systems. This research provides valuable insights into the selection and optimal design of the powertrain stages for peristaltic pumps implemented in drug delivery systems. The focus of this paper lies in the simulation and optimization of the performance of a power transmission gearbox by examining the energy consumption, sound levels, reliability, and volume as output metrics. The components of the powertrain consist of a helical gear pair for the first stage, a bevel gear pair for the second one, and finally a planetary transmission. Through extensive simulations, the model exhibits promising results, achieving an efficiency of up to 90%. Furthermore, alternative configurations were investigated to optimize the overall performance of the powertrain. This process has been simulated by employing the KISSsoft/KISSsys software package. The findings of this investigation contribute to advancements in the field of biomedical engineering and hold significant potential for improving the efficiency, reliability, and performance of drug delivery mechanisms.
format Online
Article
Text
id pubmed-10673108
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-106731082023-11-14 Design, Simulation and Multi-Objective Optimization of a Micro-Scale Gearbox for a Novel Rotary Peristaltic Pump Rogkas, Nikolaos Pelekis, Matthaios Manios, Alexandros Anastasiadis, Alexandros Vasileiou, Georgios Tsoukalis, Achilleas Manopoulos, Christos Spitas, Vasilios Micromachines (Basel) Article Peristaltic pumps are widely used in biomedical applications to ensure the safe flow of sterile or medical fluids. They are commonly employed for drug injections, IV fluids, and blood separation (apheresis). These pumps operate through a progressive contraction or expansion along a flexible tube, enabling fluid flow. They are also utilized in industrial applications for sanitary fluid transport, corrosive fluid handling, and novel pharmacological delivery systems. This research provides valuable insights into the selection and optimal design of the powertrain stages for peristaltic pumps implemented in drug delivery systems. The focus of this paper lies in the simulation and optimization of the performance of a power transmission gearbox by examining the energy consumption, sound levels, reliability, and volume as output metrics. The components of the powertrain consist of a helical gear pair for the first stage, a bevel gear pair for the second one, and finally a planetary transmission. Through extensive simulations, the model exhibits promising results, achieving an efficiency of up to 90%. Furthermore, alternative configurations were investigated to optimize the overall performance of the powertrain. This process has been simulated by employing the KISSsoft/KISSsys software package. The findings of this investigation contribute to advancements in the field of biomedical engineering and hold significant potential for improving the efficiency, reliability, and performance of drug delivery mechanisms. MDPI 2023-11-14 /pmc/articles/PMC10673108/ /pubmed/38004956 http://dx.doi.org/10.3390/mi14112099 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Rogkas, Nikolaos
Pelekis, Matthaios
Manios, Alexandros
Anastasiadis, Alexandros
Vasileiou, Georgios
Tsoukalis, Achilleas
Manopoulos, Christos
Spitas, Vasilios
Design, Simulation and Multi-Objective Optimization of a Micro-Scale Gearbox for a Novel Rotary Peristaltic Pump
title Design, Simulation and Multi-Objective Optimization of a Micro-Scale Gearbox for a Novel Rotary Peristaltic Pump
title_full Design, Simulation and Multi-Objective Optimization of a Micro-Scale Gearbox for a Novel Rotary Peristaltic Pump
title_fullStr Design, Simulation and Multi-Objective Optimization of a Micro-Scale Gearbox for a Novel Rotary Peristaltic Pump
title_full_unstemmed Design, Simulation and Multi-Objective Optimization of a Micro-Scale Gearbox for a Novel Rotary Peristaltic Pump
title_short Design, Simulation and Multi-Objective Optimization of a Micro-Scale Gearbox for a Novel Rotary Peristaltic Pump
title_sort design, simulation and multi-objective optimization of a micro-scale gearbox for a novel rotary peristaltic pump
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10673108/
https://www.ncbi.nlm.nih.gov/pubmed/38004956
http://dx.doi.org/10.3390/mi14112099
work_keys_str_mv AT rogkasnikolaos designsimulationandmultiobjectiveoptimizationofamicroscalegearboxforanovelrotaryperistalticpump
AT pelekismatthaios designsimulationandmultiobjectiveoptimizationofamicroscalegearboxforanovelrotaryperistalticpump
AT maniosalexandros designsimulationandmultiobjectiveoptimizationofamicroscalegearboxforanovelrotaryperistalticpump
AT anastasiadisalexandros designsimulationandmultiobjectiveoptimizationofamicroscalegearboxforanovelrotaryperistalticpump
AT vasileiougeorgios designsimulationandmultiobjectiveoptimizationofamicroscalegearboxforanovelrotaryperistalticpump
AT tsoukalisachilleas designsimulationandmultiobjectiveoptimizationofamicroscalegearboxforanovelrotaryperistalticpump
AT manopouloschristos designsimulationandmultiobjectiveoptimizationofamicroscalegearboxforanovelrotaryperistalticpump
AT spitasvasilios designsimulationandmultiobjectiveoptimizationofamicroscalegearboxforanovelrotaryperistalticpump