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SARS-CoV-2 Papain-like Protease Negatively Regulates the NLRP3 Inflammasome Pathway and Pyroptosis by Reducing the Oligomerization and Ubiquitination of ASC

The interaction of viruses with hosts is complex, especially so with the antiviral immune systems of hosts, and the underlying mechanisms remain perplexing. Infection with SARS-CoV-2 may result in cytokine syndrome in the later stages, reflecting the activation of the antiviral immune response. Howe...

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Detalles Bibliográficos
Autores principales: Meng, Huan, Zhou, Jianglin, Wang, Mingyu, Zheng, Mei, Xing, Yaling, Wang, Yajie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10673202/
https://www.ncbi.nlm.nih.gov/pubmed/38004809
http://dx.doi.org/10.3390/microorganisms11112799

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