Locally Advanced Adenoid Cystic Carcinoma of the Breast—A Case Report with a Review of the Literature

Breast cancer (BC) is a heterogeneous disease distinguished by four main subtypes based on the expression of estrogen, progesterone receptors, and human epidermal growth factor-2 on the cancer cells. Triple-negative breast cancer (TNBC) consists of approximately 10–20% of all BCs and is characterize...

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Autores principales: Rypel, Joanna, Kubacka, Paulina, Mykała-Cieśla, Joanna, Pająk, Jacek, Bulska-Będkowska, Weronika, Chudek, Jerzy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10673311/
https://www.ncbi.nlm.nih.gov/pubmed/38004055
http://dx.doi.org/10.3390/medicina59112005
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author Rypel, Joanna
Kubacka, Paulina
Mykała-Cieśla, Joanna
Pająk, Jacek
Bulska-Będkowska, Weronika
Chudek, Jerzy
author_facet Rypel, Joanna
Kubacka, Paulina
Mykała-Cieśla, Joanna
Pająk, Jacek
Bulska-Będkowska, Weronika
Chudek, Jerzy
author_sort Rypel, Joanna
collection PubMed
description Breast cancer (BC) is a heterogeneous disease distinguished by four main subtypes based on the expression of estrogen, progesterone receptors, and human epidermal growth factor-2 on the cancer cells. Triple-negative breast cancer (TNBC) consists of approximately 10–20% of all BCs and is characterized by a poor prognosis. Adenoid cystic carcinoma (ACC) of the breast is a rare, special type of TNBC with low metastatic potential and usually favorable prognosis. There are no established recommendations concerning systemic therapy in advanced ACC. We present a case of a 70-year-old woman with locally advanced ACC with progression after radical mastectomy, and review the literature concerning the treatment of metastatic disease focused on systemic therapy.
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spelling pubmed-106733112023-11-15 Locally Advanced Adenoid Cystic Carcinoma of the Breast—A Case Report with a Review of the Literature Rypel, Joanna Kubacka, Paulina Mykała-Cieśla, Joanna Pająk, Jacek Bulska-Będkowska, Weronika Chudek, Jerzy Medicina (Kaunas) Case Report Breast cancer (BC) is a heterogeneous disease distinguished by four main subtypes based on the expression of estrogen, progesterone receptors, and human epidermal growth factor-2 on the cancer cells. Triple-negative breast cancer (TNBC) consists of approximately 10–20% of all BCs and is characterized by a poor prognosis. Adenoid cystic carcinoma (ACC) of the breast is a rare, special type of TNBC with low metastatic potential and usually favorable prognosis. There are no established recommendations concerning systemic therapy in advanced ACC. We present a case of a 70-year-old woman with locally advanced ACC with progression after radical mastectomy, and review the literature concerning the treatment of metastatic disease focused on systemic therapy. MDPI 2023-11-15 /pmc/articles/PMC10673311/ /pubmed/38004055 http://dx.doi.org/10.3390/medicina59112005 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Rypel, Joanna
Kubacka, Paulina
Mykała-Cieśla, Joanna
Pająk, Jacek
Bulska-Będkowska, Weronika
Chudek, Jerzy
Locally Advanced Adenoid Cystic Carcinoma of the Breast—A Case Report with a Review of the Literature
title Locally Advanced Adenoid Cystic Carcinoma of the Breast—A Case Report with a Review of the Literature
title_full Locally Advanced Adenoid Cystic Carcinoma of the Breast—A Case Report with a Review of the Literature
title_fullStr Locally Advanced Adenoid Cystic Carcinoma of the Breast—A Case Report with a Review of the Literature
title_full_unstemmed Locally Advanced Adenoid Cystic Carcinoma of the Breast—A Case Report with a Review of the Literature
title_short Locally Advanced Adenoid Cystic Carcinoma of the Breast—A Case Report with a Review of the Literature
title_sort locally advanced adenoid cystic carcinoma of the breast—a case report with a review of the literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10673311/
https://www.ncbi.nlm.nih.gov/pubmed/38004055
http://dx.doi.org/10.3390/medicina59112005
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