New Steroidal Selenides as Proapoptotic Factors

Cytostatic and pro-apoptotic effects of selenium steroid derivatives against HeLa cells were determined. The highest cytostatic activity was shown by derivative 4 (GI(50) 25.0 µM, almost complete growth inhibition after three days of culture, and over 97% of apoptotic and dead cells at 200 µM). The...

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Detalles Bibliográficos
Autores principales: Jastrzebska, Izabella, Wawrusiewicz-Kurylonek, Natalia, Grześ, Paweł A., Ratkiewicz, Artur, Grabowska, Ewa, Czerniecka, Magdalena, Czyżewska, Urszula, Tylicki, Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10673341/
https://www.ncbi.nlm.nih.gov/pubmed/38005248
http://dx.doi.org/10.3390/molecules28227528

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10673341/
https://www.ncbi.nlm.nih.gov/pubmed/38005248
http://dx.doi.org/10.3390/molecules28227528

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