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New Steroidal Selenides as Proapoptotic Factors
Cytostatic and pro-apoptotic effects of selenium steroid derivatives against HeLa cells were determined. The highest cytostatic activity was shown by derivative 4 (GI(50) 25.0 µM, almost complete growth inhibition after three days of culture, and over 97% of apoptotic and dead cells at 200 µM). The...
Autores principales: | Jastrzebska, Izabella, Wawrusiewicz-Kurylonek, Natalia, Grześ, Paweł A., Ratkiewicz, Artur, Grabowska, Ewa, Czerniecka, Magdalena, Czyżewska, Urszula, Tylicki, Adam |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10673341/ https://www.ncbi.nlm.nih.gov/pubmed/38005248 http://dx.doi.org/10.3390/molecules28227528 |
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