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Transcriptome and Lipidomic Analysis Suggests Lipid Metabolism Reprogramming and Upregulating SPHK1 Promotes Stemness in Pancreatic Ductal Adenocarcinoma Stem-like Cells

Cancer stem cells (CSCs) are considered to play a key role in the development and progression of pancreatic ductal adenocarcinoma (PDAC). However, little is known about lipid metabolism reprogramming in PDAC CSCs. Here, we assigned stemness indices, which were used to describe and quantify CSCs, to...

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Detalles Bibliográficos
Autores principales:	Xu, Jinzhi, Zhou, Lina, Du, Xiaojing, Qi, Zhuoran, Chen, Sinuo, Zhang, Jian, Cao, Xin, Xia, Jinglin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10673379/ https://www.ncbi.nlm.nih.gov/pubmed/37999228 http://dx.doi.org/10.3390/metabo13111132

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