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Deployable Lab-on-a-Chip Sensor for Colorimetric Measurements

The infield measurement of nutrients, heavy metals, and other contaminants in water is still a needed tool in environmental sciences. The Lab-on-a-chip approach can develop deployable instruments that use the standardized analytical assay in a miniaturized manner in the field. This paper presents a...

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Autores principales: Gassmann, Stefan, Schleifer, Till, Schuette, Helmut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10673530/
https://www.ncbi.nlm.nih.gov/pubmed/38004959
http://dx.doi.org/10.3390/mi14112102
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author Gassmann, Stefan
Schleifer, Till
Schuette, Helmut
author_facet Gassmann, Stefan
Schleifer, Till
Schuette, Helmut
author_sort Gassmann, Stefan
collection PubMed
description The infield measurement of nutrients, heavy metals, and other contaminants in water is still a needed tool in environmental sciences. The Lab-on-a-chip approach can develop deployable instruments that use the standardized analytical assay in a miniaturized manner in the field. This paper presents a Lab-on-a-chip platform for colorimetric measurements that can be deployed for nutrient monitoring in open water (oceans, rivers, lakes, etc.). Nitrite was selected as an analyte. Change to other analytes is possible by changing the reagents and the detection wavelength. In this paper, the principle of the sensor, technical realization, setup of the sensor, and test deployment are described. The sensor prototype was deployed at the Jade Bay (German Bight) for 9 h, measuring the nitrite value every 20 min. Reference samples were taken and processed in the lab. The work presented here shows that an infield measurement using a colorimetric assay is possible by applying Lab-on-a-chip principles.
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spelling pubmed-106735302023-11-16 Deployable Lab-on-a-Chip Sensor for Colorimetric Measurements Gassmann, Stefan Schleifer, Till Schuette, Helmut Micromachines (Basel) Article The infield measurement of nutrients, heavy metals, and other contaminants in water is still a needed tool in environmental sciences. The Lab-on-a-chip approach can develop deployable instruments that use the standardized analytical assay in a miniaturized manner in the field. This paper presents a Lab-on-a-chip platform for colorimetric measurements that can be deployed for nutrient monitoring in open water (oceans, rivers, lakes, etc.). Nitrite was selected as an analyte. Change to other analytes is possible by changing the reagents and the detection wavelength. In this paper, the principle of the sensor, technical realization, setup of the sensor, and test deployment are described. The sensor prototype was deployed at the Jade Bay (German Bight) for 9 h, measuring the nitrite value every 20 min. Reference samples were taken and processed in the lab. The work presented here shows that an infield measurement using a colorimetric assay is possible by applying Lab-on-a-chip principles. MDPI 2023-11-16 /pmc/articles/PMC10673530/ /pubmed/38004959 http://dx.doi.org/10.3390/mi14112102 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Gassmann, Stefan
Schleifer, Till
Schuette, Helmut
Deployable Lab-on-a-Chip Sensor for Colorimetric Measurements
title Deployable Lab-on-a-Chip Sensor for Colorimetric Measurements
title_full Deployable Lab-on-a-Chip Sensor for Colorimetric Measurements
title_fullStr Deployable Lab-on-a-Chip Sensor for Colorimetric Measurements
title_full_unstemmed Deployable Lab-on-a-Chip Sensor for Colorimetric Measurements
title_short Deployable Lab-on-a-Chip Sensor for Colorimetric Measurements
title_sort deployable lab-on-a-chip sensor for colorimetric measurements
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10673530/
https://www.ncbi.nlm.nih.gov/pubmed/38004959
http://dx.doi.org/10.3390/mi14112102
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