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Study Models of Drug–Drug Interactions Involving P-Glycoprotein: The Potential Benefit of P-Glycoprotein Modulation at the Kidney and Intestinal Levels
P-glycoprotein (P-gp) is a crucial membrane transporter situated on the cell’s apical surface, being responsible for eliminating xenobiotics and endobiotics. P-gp modulators are compounds that can directly or indirectly affect this protein, leading to changes in its expression and function. These mo...
Autores principales: | Veiga-Matos, Jéssica, Morales, Ana I., Prieto, Marta, Remião, Fernando, Silva, Renata |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10673607/ https://www.ncbi.nlm.nih.gov/pubmed/38005253 http://dx.doi.org/10.3390/molecules28227532 |
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