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SGC-CLK-1: A chemical probe for the Cdc2-like kinases CLK1, CLK2, and CLK4

Small molecule modulators are important tools to study both basic biology and the complex signaling of protein kinases. The cdc2-like kinases (CLK) are a family of four kinases that have garnered recent interest for their involvement in a diverse set of diseases such as neurodegeneration, autoimmuni...

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Detalles Bibliográficos
Autores principales: Tiek, Deanna, Wells, Carrow I., Schröder, Martin, Song, Xiao, Alamillo-Ferrer, Carla, Goenka, Anshika, Iglesia, Rebeca, Lu, Minghui, Hu, Bo, Kwarcinski, Frank, Sintha, Parvathi, de Silva, Chandi, Hossain, Mohammad Anwar, Picado, Alfredo, Zuercher, William, Zutshi, Reena, Knapp, Stefan, Riggins, Rebecca B., Cheng, Shi-Yuan, Drewry, David H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10673624/
https://www.ncbi.nlm.nih.gov/pubmed/38009092
http://dx.doi.org/10.1016/j.crchbi.2023.100045