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Introducing Data Sciences to N-of-1 Designs, Statistics, Use-Cases, the Future, and the Moniker ‘N-of-1’ Trial

This article, an introduction to HDSR’s “Personalized (N-of-1) Trials: Methods, Applications, and Impact” special issue, describes the rationale for a primer of the methods, data types and management, designs, and use cases for personalized (N-of-1) trials. It explains that the design and implementa...

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Detalles Bibliográficos
Autores principales: Davidson, Karina W., Cheung, Ying Kuen, Friel, Ciarán P., Suls, Jerry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10673636/
https://www.ncbi.nlm.nih.gov/pubmed/38009132
http://dx.doi.org/10.1162/99608f92.116c43fe
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author Davidson, Karina W.
Cheung, Ying Kuen
Friel, Ciarán P.
Suls, Jerry
author_facet Davidson, Karina W.
Cheung, Ying Kuen
Friel, Ciarán P.
Suls, Jerry
author_sort Davidson, Karina W.
collection PubMed
description This article, an introduction to HDSR’s “Personalized (N-of-1) Trials: Methods, Applications, and Impact” special issue, describes the rationale for a primer of the methods, data types and management, designs, and use cases for personalized (N-of-1) trials. It explains that the design and implementation of personalized (N-of-1) trials is only useful if patients volunteer for research involving them and actively participate in clinical services that use them. However, ‘N-of-1 trials’ may be an inadequate name to enact such patient engagement. The authors briefly review what patients have reported about the ‘N-of-1’ label and propose a more consumer-friendly moniker for this type of research and clinical approach to improve evidence-based science.
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spelling pubmed-106736362023-11-24 Introducing Data Sciences to N-of-1 Designs, Statistics, Use-Cases, the Future, and the Moniker ‘N-of-1’ Trial Davidson, Karina W. Cheung, Ying Kuen Friel, Ciarán P. Suls, Jerry Harv Data Sci Rev Article This article, an introduction to HDSR’s “Personalized (N-of-1) Trials: Methods, Applications, and Impact” special issue, describes the rationale for a primer of the methods, data types and management, designs, and use cases for personalized (N-of-1) trials. It explains that the design and implementation of personalized (N-of-1) trials is only useful if patients volunteer for research involving them and actively participate in clinical services that use them. However, ‘N-of-1 trials’ may be an inadequate name to enact such patient engagement. The authors briefly review what patients have reported about the ‘N-of-1’ label and propose a more consumer-friendly moniker for this type of research and clinical approach to improve evidence-based science. 2022 2022-09-08 /pmc/articles/PMC10673636/ /pubmed/38009132 http://dx.doi.org/10.1162/99608f92.116c43fe Text en https://creativecommons.org/licenses/by/4.0/This editorial is licensed under a Creative Commons Attribution (CC BY 4.0) International license (https://creativecommons.org/licenses/by/4.0/) , except where otherwise indicated with respect to particular material included in the editorial.
spellingShingle Article
Davidson, Karina W.
Cheung, Ying Kuen
Friel, Ciarán P.
Suls, Jerry
Introducing Data Sciences to N-of-1 Designs, Statistics, Use-Cases, the Future, and the Moniker ‘N-of-1’ Trial
title Introducing Data Sciences to N-of-1 Designs, Statistics, Use-Cases, the Future, and the Moniker ‘N-of-1’ Trial
title_full Introducing Data Sciences to N-of-1 Designs, Statistics, Use-Cases, the Future, and the Moniker ‘N-of-1’ Trial
title_fullStr Introducing Data Sciences to N-of-1 Designs, Statistics, Use-Cases, the Future, and the Moniker ‘N-of-1’ Trial
title_full_unstemmed Introducing Data Sciences to N-of-1 Designs, Statistics, Use-Cases, the Future, and the Moniker ‘N-of-1’ Trial
title_short Introducing Data Sciences to N-of-1 Designs, Statistics, Use-Cases, the Future, and the Moniker ‘N-of-1’ Trial
title_sort introducing data sciences to n-of-1 designs, statistics, use-cases, the future, and the moniker ‘n-of-1’ trial
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10673636/
https://www.ncbi.nlm.nih.gov/pubmed/38009132
http://dx.doi.org/10.1162/99608f92.116c43fe
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