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Improved in situ characterization of protein complex dynamics at scale with thermal proximity co-aggregation
Cellular activities are carried out vastly by protein complexes but large repertoire of protein complexes remains functionally uncharacterized which necessitate new strategies to delineate their roles in various cellular processes and diseases. Thermal proximity co-aggregation (TPCA) is readily depl...
Autores principales: | Sun, Siyuan, Zheng, Zhenxiang, Wang, Jun, Li, Fengming, He, An, Lai, Kunjia, Zhang, Shuang, Lu, Jia-Hong, Tian, Ruijun, Tan, Chris Soon Heng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10673876/ https://www.ncbi.nlm.nih.gov/pubmed/38001062 http://dx.doi.org/10.1038/s41467-023-43526-2 |
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