IL-1β-mediated adaptive reprogramming of endogenous human cardiac fibroblasts to cells with immune features during fibrotic remodeling

The source and roles of fibroblasts and T-cells during maladaptive remodeling and myocardial fibrosis in the setting of pulmonary arterial hypertension (PAH) have been long debated. We demonstrate, using single-cell mass cytometry, a subpopulation of endogenous human cardiac fibroblasts expressing i...

Descripción completa

Detalles Bibliográficos
Autores principales: Siamwala, Jamila H., Pagano, Francesco S., Dubielecka, Patrycja M., Ivey, Malina J., Guirao-Abad, Jose Pedro, Zhao, Alexander, Chen, Sonja, Granston, Haley, Jeong, Jae Yun, Rounds, Sharon, Kanisicak, Onur, Sadayappan, Sakthivel, Gilbert, Richard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10673909/
https://www.ncbi.nlm.nih.gov/pubmed/38001239
http://dx.doi.org/10.1038/s42003-023-05463-0

Ejemplares similares

Ejemplares similares