In vivo imaging of mitochondrial DNA mutations using an integrated nano Cas12a sensor

Mutations in mitochondrial DNA (mtDNA) play critical roles in many human diseases. In vivo visualization of cells bearing mtDNA mutations is important for resolving the complexity of these diseases, which remains challenging. Here we develop an integrated nano Cas12a sensor (InCasor) and show its ut...

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Detalles Bibliográficos
Autores principales: Li, Yanan, Wu, Yonghua, Xu, Ru, Guo, Jialing, Quan, Fenglei, Zhang, Yongyuan, Huang, Di, Pei, Yiran, Gao, Hua, Liu, Wei, Liu, Junjie, Zhang, Zhenzhong, Deng, Ruijie, Shi, Jinjin, Zhang, Kaixiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10673915/
https://www.ncbi.nlm.nih.gov/pubmed/38001092
http://dx.doi.org/10.1038/s41467-023-43552-0

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