Nanoparticles exhibiting virus-mimic surface topology for enhanced oral delivery

The oral delivery of nano-drug delivery systems (Nano-DDS) remains a challenge. Taking inspirations from viruses, here we construct core–shell mesoporous silica nanoparticles (NPs, ~80 nm) with virus-like nanospikes (VSN) to simulate viral morphology, and further modified VSN with L-alanine (CVSN) t...

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Detalles Bibliográficos
Autores principales: Sang, Zhentao, Xu, Lu, Ding, Renyu, Wang, Minjun, Yang, Xiaoran, Li, Xitan, Zhou, Bingxin, Gou, Kaijun, Han, Yang, Liu, Tingting, Chen, Xuchun, Cheng, Ying, Yang, Huazhe, Li, Heran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10673925/
https://www.ncbi.nlm.nih.gov/pubmed/38001086
http://dx.doi.org/10.1038/s41467-023-43465-y

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