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Regulating NLRP3 Inflammasome–Induced Pyroptosis via Nrf2: TBHQ Limits Hyperoxia-Induced Lung Injury in a Mouse Model of Bronchopulmonary Dysplasia

Nuclear factor e2–related factor 2 (Nrf2) plays a key role in cellular resistance to oxidative stress injury. Oxidative stress injury, caused by Nrf2 imbalance, results in increased pyroptosis, DNA damage, and inflammatory activation, which may lead to the arrest of alveolar development and bronchop...

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Detalles Bibliográficos
Autores principales: Wang, Minrong, Zhang, Feng, Ning, Xuemei, Wu, Chan, Zhou, Yue, Gou, Zhixian, Fan, Yang, Duan, Rongrong, Li, Zhongni, Shao, Chunyan, Lu, Liqun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10673969/
https://www.ncbi.nlm.nih.gov/pubmed/37556072
http://dx.doi.org/10.1007/s10753-023-01885-4