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Regulating NLRP3 Inflammasome–Induced Pyroptosis via Nrf2: TBHQ Limits Hyperoxia-Induced Lung Injury in a Mouse Model of Bronchopulmonary Dysplasia
Nuclear factor e2–related factor 2 (Nrf2) plays a key role in cellular resistance to oxidative stress injury. Oxidative stress injury, caused by Nrf2 imbalance, results in increased pyroptosis, DNA damage, and inflammatory activation, which may lead to the arrest of alveolar development and bronchop...
Autores principales: | Wang, Minrong, Zhang, Feng, Ning, Xuemei, Wu, Chan, Zhou, Yue, Gou, Zhixian, Fan, Yang, Duan, Rongrong, Li, Zhongni, Shao, Chunyan, Lu, Liqun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10673969/ https://www.ncbi.nlm.nih.gov/pubmed/37556072 http://dx.doi.org/10.1007/s10753-023-01885-4 |
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